HitPredict

Interactor 1: GLRX3 (O76003)
Glutaredoxin-3 (PKC-interacting cousin of thioredoxin) (PICOT) (PKC-theta-interacting protein) (PKCq-interacting protein) (Thioredoxin-like protein 2)
Gene: GLRX3

Interactor 2: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	34591642
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 335 Hs			1 1367
+	Hs
		411391 PDIA6_HUMAN (1-251): 7.84e-38: 141: 14.78		INSR_HUMAN (32-1365): 0: 1219: 56.54
+	Rn
		544870 PDIA6_RAT (1-251): 1.9e-38: 143: 15.12		INSR_RAT (20-1365): 0: 1210: 55.45
+	Hs
		411442 TXND5_HUMAN (5-115): 4.2e-28: 114: 19.83		INSR_HUMAN (32-1365): 0: 1219: 56.54
+	Hs
		411285 PDIA4_HUMAN (1-115): 7.77e-24: 104: 19.67		INSR_HUMAN (32-1365): 0: 1219: 56.54
+	Rn
		388065 PDIA1_RAT (1-144): 2.21e-24: 105: 18.00		INSR_RAT (20-1365): 0: 1210: 55.45
+	Hs
		537760 TXND5_HUMAN (5-115): 4.2e-28: 114: 19.83		INSRR_HUMAN (14-1310): 0: 1170: 55.26
+	At
		83488 TRXH3_ARATH (8-117): 2.05e-37: 131: 28.57		Y1756_ARATH (467-1285): 0: 611: 14.95
+	At
		1114780 TRXH3_ARATH (8-117): 2.05e-37: 131: 28.57		Y5188_ARATH (430-1303): 0: 598: 14.54
+	At
		84146 TRXH5_ARATH (27-122): 1.19e-38: 135: 31.25		Y2289_ARATH (490-1298): 0: 577: 13.42
+	At
		83442 TRXH5_ARATH (27-122): 1.19e-38: 135: 31.25		Y1755_ARATH (494-1295): 0: 563: 16.93
+	Hs
		280338 GLRX3_HUMAN (18-335): 4.6e-102: 305: 100.00		NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61
+	Hs
		384875 PDIA6_HUMAN (1-251): 7.84e-38: 141: 14.78		NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61
+	Hs
		202575 TXNL1_HUMAN (12-258): 1.31e-37: 137: 20.08		NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61
+	Hs
		384156 THIO_HUMAN (13-116): 4.03e-37: 130: 26.92		NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61
+	Hs
		1067715 PDIA6_HUMAN (1-251): 7.84e-38: 141: 14.78		NTRK3_HUMAN (977-1262): 5.74e-64: 236: 39.16
+	Hs
		385177 TXND5_HUMAN (5-115): 4.2e-28: 114: 19.83		NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61
+	Hs
		674480 TXND5_HUMAN (5-115): 4.2e-28: 114: 19.83		UFO_HUMAN (790-1271): 9.27e-68: 249: 32.10
+	Hs
		384191 PDIA4_HUMAN (1-115): 7.77e-24: 104: 19.67		NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61
+	Hs
		495464 THIO_HUMAN (13-116): 4.03e-37: 130: 26.92		ERBB3_HUMAN (15-362): 5.41e-25: 115: 18.88
+	Zm
		111798 K7UQQ8_MAIZE (89-221): 2.78e-38: 135: 29.32		K7W777_MAIZE (821-911): 2.22e-09: 64.3: 9.00