HitPredict

Interactor 1: KRT34 (O76011)
Keratin, type I cuticular Ha4 (Hair keratin, type I Ha4) (Keratin-34) (K34)
Gene: KRT34

Interactor 2: SHPS1 (P78324)
Tyrosine-protein phosphatase non-receptor type substrate 1 (SHP substrate 1) (SHPS-1) (Brain Ig-like molecule with tyrosine-based activation motifs) (Bit) (CD172 antigen-like family member A) (Inhibitory receptor SHPS-1) (Macrophage fusion receptor) (MyD-1 antigen) (Signal-regulatory protein alpha-1) (Sirp-alpha-1) (Signal-regulatory protein alpha-2) (Sirp-alpha-2) (Signal-regulatory protein alpha-3) (Sirp-alpha-3) (p84) (CD antigen CD172a)
Gene: SIRPA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.439

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 394 Hs			1 504
+	Hs
		941696 K1C40_HUMAN (4-387): 5.61e-144: 417: 63.68		SHPS1_HUMAN (1-504): 4.62e-114: 348: 100.00
+	Hs
		580011 K1C15_HUMAN (55-367): 4.97e-105: 319: 56.69		SHPS1_HUMAN (1-504): 4.62e-114: 348: 100.00
+	Hs
		941694 K1H1_HUMAN (1-393): 5.22e-80: 253: 88.80		SHPS1_HUMAN (1-504): 4.62e-114: 348: 100.00
+	Hs
		1061304 K1C40_HUMAN (4-387): 5.61e-144: 417: 63.68		OPCM_HUMAN (136-453): 8.28e-27: 112: 9.97
+	Hs
		66240 K1C40_HUMAN (4-387): 5.61e-144: 417: 63.68		A8K0Y0_HUMAN (136-453): 8.28e-27: 112: 9.97
+	Hs
		353599 K1C14_HUMAN (54-367): 9.08e-140: 408: 58.92		IGHG1_HUMAN (3-248): 3.88e-18: 88.3: 17.89
+	Hs
		353619 K1C16_HUMAN (54-381): 2.74e-107: 325: 56.71		IGHG1_HUMAN (3-248): 3.88e-18: 88.3: 17.89
+	Hs
		353600 K2C6A_HUMAN (19-391): 1.07e-80: 259: 23.73		IGHG1_HUMAN (3-248): 3.88e-18: 88.3: 17.89
+	Hs
		353629 K2C5_HUMAN (19-377): 5.17e-80: 258: 24.65		IGHG1_HUMAN (3-248): 3.88e-18: 88.3: 17.89