HitPredict

Interactor 1: KRT36 (O76013)
Keratin, type I cuticular Ha6 (Hair keratin, type I Ha6) (Keratin-36) (K36)
Gene: KRT36

Interactor 2: K2C3 (P12035)
Keratin, type II cytoskeletal 3 (65 kDa cytokeratin) (Cytokeratin-3) (CK-3) (Keratin-3) (K3) (Type-II keratin Kb3)
Gene: KRT3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Filament~Filament
Common GO terms GO:0005829 - cytosol
GO:0030280 - structural constituent of skin epidermis
GO:0030855 - epithelial cell differentiation
GO:0045095 - keratin filament
GO:0045109 - intermediate filament organization
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024