HitPredict

Interactor 1: KRT37 (O76014)
Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7) (Keratin-37) (K37)
Gene: KRT37

Interactor 2: RUFY3 (Q7L099)
Protein RUFY3 (RUN and FYVE domain-containing protein 3) (Rap2-interacting protein x) (RIPx) (Single axon-regulated protein) (Singar)
Gene: RUFY3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 449 Hs			1 469
+	Hs
		444404 K1C19_HUMAN (100-412): 1.84e-96: 297: 49.20		RUFY3_HUMAN (1-469): 2.74e-116: 351: 100.00
+	Hs
		280911 KRT37_HUMAN (1-449): 1.6e-85: 270: 100.00		RUFY1_HUMAN (60-467): 1.53e-71: 241: 55.21
+	Hs
		528413 K1C40_HUMAN (1-437): 1.98e-153: 443: 50.23		MYH8_HUMAN (194-466): 1.04e-09: 63.3: 12.09
+	Hs
		522624 K1C40_HUMAN (1-437): 1.98e-153: 443: 50.23		MYH7_HUMAN (48-469): 1.55e-09: 62.6: 11.11
+	Hs
		1149413 K1C40_HUMAN (1-437): 1.98e-153: 443: 50.23		MYH4_HUMAN (64-466): 4.64e-09: 61: 12.77
+	Hs
		1149398 K1C40_HUMAN (1-437): 1.98e-153: 443: 50.23		MYH2_HUMAN (73-466): 7.27e-09: 60.6: 9.90
+	Hs
		502919 K1C40_HUMAN (1-437): 1.98e-153: 443: 50.23		MYH3_HUMAN (181-465): 5.86e-09: 60.6: 11.71
+	Hs
		522555 K1C40_HUMAN (1-437): 1.98e-153: 443: 50.23		MYH1_HUMAN (64-466): 8.42e-09: 60.3: 12.29
+	Hs
		213982 KRT86_HUMAN (3-446): 5.72e-90: 283: 25.89		FYCO1_HUMAN (70-465): 4.58e-62: 220: 18.32
+	Hs
		281051 KRT38_HUMAN (1-428): 9.91e-82: 261: 94.39		FYCO1_HUMAN (70-465): 4.58e-62: 220: 18.32
+	Hs
		1062064 K2C72_HUMAN (13-448): 7.72e-77: 250: 23.69		FYCO1_HUMAN (70-465): 4.58e-62: 220: 18.32
+	Hs
		725143 K1C17_HUMAN (100-415): 4.68e-97: 300: 51.90		MYH10_HUMAN (249-467): 4.89e-42: 162: 15.53
+	Hs
		724787 K1C17_HUMAN (100-415): 4.68e-97: 300: 51.90		MYH9_HUMAN (236-467): 2.43e-34: 139: 15.09
+	Hs
		280875 KRT37_HUMAN (1-449): 1.6e-85: 270: 100.00		LIPA1_HUMAN (52-469): 7.69e-43: 164: 15.28
+	Hs
		64599 K1C39_HUMAN (92-446): 2.6e-110: 335: 57.26		MYH7B_HUMAN (187-466): 3.11e-11: 68: 11.57
+	Hs
		49550 A1A4E9_HUMAN (93-421): 1.6e-93: 291: 50.15		MYH1_HUMAN (64-466): 8.42e-09: 60.3: 12.29
+	Hs
		522534 K1C13_HUMAN (93-421): 1.73e-93: 291: 50.15		MYH1_HUMAN (64-466): 8.42e-09: 60.3: 12.29