HitPredict

Interactor 1: KRT38 (O76015)
Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8) (Keratin-38) (K38)
Gene: KRT38

Interactor 2: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	29892012, 25416956, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 456 Hs			1 406
+	Hs
		798662 KT33B_HUMAN (68-444): 1.57e-160: 461: 64.32		PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86
+	Hs
		907065 K1C40_HUMAN (1-452): 5.43e-115: 346: 49.23		PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00
+	Hs
		580008 K1C15_HUMAN (103-415): 4.26e-96: 298: 52.70		PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00
+	Hs
		907039 K1H1_HUMAN (55-429): 2.44e-88: 277: 63.47		PRS8_HUMAN (1-406): 1.42e-136: 398: 100.00
+	Hs
		444333 K1C19_HUMAN (100-412): 8.65e-100: 306: 50.48		PRS6B_HUMAN (1-399): 6.4e-122: 361: 41.86
+	Hs
		444327 K1C19_HUMAN (100-412): 8.65e-100: 306: 50.48		PRS7_HUMAN (84-392): 1.21e-115: 345: 56.31