Interactor 1: CLPX (O76031)
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial
Gene: CLPX

Interactor 2: CLPP (Q16740)
ATP-dependent Clp protease proteolytic subunit, mitochondrial (EC 3.4.21.92) (Endopeptidase Clp)
Gene: CLPP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.912

The method score is based on:

Property Details
Experiments 11923310, 26058080, 32628020, 27389535, 15522782
Identification Methods pull down, proximity labelling technology, anti bait coimmunoprecipitation, filter binding
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_2~CLP_protease
Common GO terms GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006508 - proteolysis
GO:0009368 - endopeptidase Clp complex
GO:0051603 - proteolysis involved in protein catabolic process
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 633
Hs

1 277
+ Dm
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024