Interactor 1: CDKL5 (O76039)
Cyclin-dependent kinase-like 5 (EC 2.7.11.22) (Serine/threonine-protein kinase 9)
Gene: CDKL5

Interactor 2: KGP2 (Q13237)
cGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)
Gene: PRKG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 23602568
Identification Methods affinity chromatography technology, tandem affinity purification
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~cNMP_binding, Pkinase~Pkinase
Common GO terms GO:0004672 - protein kinase activity
GO:0005524 - ATP binding
GO:0006468 - protein phosphorylation
GO:0106310 - protein serine kinase activity
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 960
Hs

1 762
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Last updated: 15 Jul 2024