HitPredict

Interactor 1: NEBL (O76041)
Nebulette (Actin-binding Z-disk protein)
Gene: NEBL

Interactor 2: TAU (P10636)
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Gene: MAPT

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	35063084
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1014 Hs			1 758
+	Hs
		497800 PACN2_HUMAN (634-1013): 2.14e-44: 170: 15.05		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497550 PACN1_HUMAN (634-1013): 1.44e-42: 163: 15.93		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		496988 SPTN1_HUMAN (359-1013): 4.51e-39: 160: 11.50		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497507 SH3G2_HUMAN (646-1013): 2.86e-34: 137: 15.18		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Hs
		497761 DBNL_HUMAN (787-1013): 6.14e-30: 125: 20.71		TAU_HUMAN (1-758): 3.6e-89: 298: 100.00
+	Rn
		555250 SPTN1_RAT (359-1013): 6.99e-39: 160: 11.65		TAU_RAT (1-758): 4.86e-75: 260: 71.47
+	Rn
		94140 SPTN1_RAT (359-1013): 6.99e-39: 160: 11.65		F1LST4_RAT (1-757): 8.59e-75: 260: 71.56
+	Mm
		498047 PACN1_MOUSE (634-1013): 4.61e-42: 162: 14.88		TAU_MOUSE (1-758): 1.4e-69: 244: 70.17
+	Hs
		203224 MYO1E_HUMAN (473-1013): 1.11e-48: 190: 11.81		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76
+	Sp
		194039 MYO1_SCHPO (462-1012): 5.36e-40: 163: 11.25		YFHH_SCHPO (5-755): 4.88e-12: 72: 8.72
+	Hs
		203262 PACN2_HUMAN (634-1013): 2.14e-44: 170: 15.05		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76
+	Hs
		203251 PACN1_HUMAN (634-1013): 1.44e-42: 163: 15.93		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76
+	Rn
		192356 SH3G3_RAT (781-1013): 1.34e-35: 140: 16.40		SYNJ1_RAT (72-557): 4.95e-13: 75: 12.10
+	Mm
		88460 SH3G3_MOUSE (781-1013): 1.86e-35: 140: 16.40		D3Z656_MOUSE (72-555): 1.33e-11: 70.4: 11.56
+	Rn
		192354 SH3G2_RAT (646-1013): 2.01e-33: 134: 14.63		SYNJ1_RAT (72-557): 4.95e-13: 75: 12.10
+	Rn
		193638 SH3G1_RAT (808-1013): 5.16e-32: 130: 16.43		SYNJ1_RAT (72-557): 4.95e-13: 75: 12.10
+	Mm
		88459 SH3G2_MOUSE (646-1013): 2.47e-33: 134: 14.63		D3Z656_MOUSE (72-555): 1.33e-11: 70.4: 11.56
+	Hs
		203249 SH3G2_HUMAN (646-1013): 2.86e-34: 137: 15.18		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76
+	Hs
		203260 PACN3_HUMAN (634-1013): 9.6e-34: 137: 15.41		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76
+	Hs
		203248 SH3G1_HUMAN (808-1013): 1.7e-29: 123: 15.02		SYNJ1_HUMAN (7-411): 1.53e-09: 63.9: 9.76