HitPredict

Interactor 1: NEBL (O76041)
Nebulette (Actin-binding Z-disk protein)
Gene: NEBL

Interactor 2: ZO1 (Q07157)
Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1)
Gene: TJP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_2~SH3_9
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1014 Hs			1 1748
+	Hs
		990838 SPTN1_HUMAN (359-1013): 4.51e-39: 160: 11.50		ZO1_HUMAN (1-1748): 0: 925: 100.00
+	Mm
		761854 SRC8_MOUSE (523-1012): 2.21e-39: 156: 13.28		ZO1_MOUSE (1-1748): 0: 874: 90.79
+	Hs
		990858 SH319_HUMAN (954-1013): 1.61e-16: 86.6: 41.67		ZO1_HUMAN (1-1748): 0: 925: 100.00
+	Hs
		990840 SRC8_HUMAN (284-641): 3.71e-12: 72.1: 14.37		ZO1_HUMAN (1-1748): 0: 925: 100.00
+	Hs
		282374 NEBL_HUMAN (1-1014): 0: 665: 100.00		ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98
+	Dm
		1363696 Q9VDF4_DROME (501-1013): 2.49e-39: 156: 14.13		Q9VHK4_DROME (14-1358): 1.93e-170: 556: 26.59
+	Dm
		331926 O96046_DROME (501-1013): 6.95e-41: 161: 14.50		Q7K4E2_DROME (14-817): 1.81e-171: 547: 35.04
+	Mm
		1142986 PACN1_MOUSE (634-1013): 4.61e-42: 162: 14.88		DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92
+	Mm
		561163 SPTN1_MOUSE (359-1013): 6.7e-39: 160: 11.65		DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92
+	Mm
		1143327 SH3G2_MOUSE (646-1013): 2.47e-33: 134: 14.63		DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92
+	Mm
		1143326 SRBS1_MOUSE (913-1013): 1.21e-11: 71.2: 30.39		DLG4_MOUSE (1-112): 2.37e-27: 122: 29.92
+	Hs
		235554 VINEX_HUMAN (858-1010): 1.08e-13: 77.3: 27.45		DLG5_HUMAN (262-508): 3.83e-17: 90.3: 21.43
+	Hs
		1052264 SRC8_HUMAN (284-641): 3.71e-12: 72.1: 14.37		DLG5_HUMAN (262-508): 3.83e-17: 90.3: 21.43
+	Hs
		1060075 LASP1_HUMAN (496-672): 7.48e-19: 89.4: 25.14		ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98
+	Hs
		1126376 SH319_HUMAN (954-1013): 1.61e-16: 86.6: 41.67		ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98
+	Hs
		1314994 SRBS1_HUMAN (881-1013): 1.5e-10: 67.7: 24.81		ZO2_HUMAN (391-610): 1e-09: 65.7: 17.98