HitPredict

Interactor 1: NEBL (O76041)
Nebulette (Actin-binding Z-disk protein)
Gene: NEBL

Interactor 2: ZYX (Q15942)
Zyxin (Zyxin-2)
Gene: ZYX

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	15004028, 34079125, 11423549
Identification Methods	two hybrid, pull down, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001725 - stress fiber
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1014 Hs			1 572
+	Hs
		282330 NEBL_HUMAN (1-1014): 0: 665: 100.00		FHL3_HUMAN (410-544): 1.63e-09: 61.2: 28.99
+	Hs
		1078829 ITSN1_HUMAN (364-1012): 1.76e-19: 96.9: 11.30		ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00
+	Hs
		1059978 LASP1_HUMAN (496-672): 7.48e-19: 89.4: 25.14		ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00
+	Hs
		1080682 SH319_HUMAN (954-1013): 1.61e-16: 86.6: 41.67		ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00
+	Mm
		1143127 LASP1_MOUSE (312-451): 4.09e-21: 96.2: 30.00		ZYX_MOUSE (1-572): 3.2e-62: 216: 85.02
+	Hs
		1080768 SRBS1_HUMAN (881-1013): 1.5e-10: 67.7: 24.81		ZYX_HUMAN (1-572): 1.68e-71: 241: 100.00
+	Hs
		1045557 SPTN1_HUMAN (359-1013): 4.51e-39: 160: 11.50		TES_HUMAN (345-499): 3.83e-20: 95.1: 17.28
+	Hs
		1355075 DBNL_HUMAN (787-1013): 6.14e-30: 125: 20.71		TES_HUMAN (345-499): 3.83e-20: 95.1: 17.28
+	Hs
		823393 SRC8_HUMAN (284-641): 3.71e-12: 72.1: 14.37		PAXI_HUMAN (8-500): 3.72e-32: 132: 12.12
+	Hs
		823484 SRBS1_HUMAN (881-1013): 1.5e-10: 67.7: 24.81		PAXI_HUMAN (8-500): 3.72e-32: 132: 12.12
+	Hs
		1060077 LASP1_HUMAN (496-672): 7.48e-19: 89.4: 25.14		TES_HUMAN (345-499): 3.83e-20: 95.1: 17.28
+	Hs
		1078892 ITSN1_HUMAN (364-1012): 1.76e-19: 96.9: 11.30		AJUBA_HUMAN (9-499): 2.93e-13: 74.3: 11.33
+	Hs
		596196 NEBU_HUMAN (281-878): 2.26e-21: 103: 20.16		LIMS1_HUMAN (383-566): 1.09e-10: 65.1: 25.95
+	Mm
		1143132 LASP1_MOUSE (312-451): 4.09e-21: 96.2: 30.00		LPP_MOUSE (4-495): 2.47e-12: 71.6: 15.71
+	Hs
		1052344 SRC8_HUMAN (284-641): 3.71e-12: 72.1: 14.37		TES_HUMAN (345-499): 3.83e-20: 95.1: 17.28
+	Hs
		1060028 LASP1_HUMAN (496-672): 7.48e-19: 89.4: 25.14		LPP_HUMAN (4-495): 1.9e-13: 75.1: 13.92
+	Hs
		1044592 LASP1_HUMAN (496-672): 7.48e-19: 89.4: 25.14		FHL3_HUMAN (410-544): 1.63e-09: 61.2: 28.99