HitPredict

Interactor 1: NEBL (O76041)
Nebulette (Actin-binding Z-disk protein)
Gene: NEBL

Interactor 2: HOME3 (Q9NSC5)
Homer protein homolog 3 (Homer-3)
Gene: HOMER3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.523

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1014 Hs			1 361
+	Hs
		282318 NEBL_HUMAN (1-1014): 0: 665: 100.00		VASP_HUMAN (4-170): 7.18e-35: 133: 23.12
+	Hs
		61738 A6H8W8_HUMAN (186-1013): 1.24e-76: 278: 12.35		EP15R_HUMAN (78-354): 2.27e-57: 201: 14.74
+	Mm
		561177 SPTN1_MOUSE (359-1013): 6.7e-39: 160: 11.65		HOME1_MOUSE (4-360): 1.28e-89: 275: 48.92
+	Mm
		82779 B9EKJ1_MOUSE (359-1013): 5.69e-39: 160: 11.65		HOME1_MOUSE (4-360): 1.28e-89: 275: 48.92
+	Hs
		1205738 DBNL_HUMAN (787-1013): 6.14e-30: 125: 20.71		HOME1_HUMAN (4-360): 1.39e-87: 269: 50.42
+	Hs
		61732 A6H8W8_HUMAN (186-1013): 1.24e-76: 278: 12.35		EPS15_HUMAN (78-327): 1.5e-16: 83.1: 13.31
+	Hs
		1349279 ITSN2_HUMAN (412-1011): 8.62e-21: 101: 15.16		EP15R_HUMAN (78-354): 2.27e-57: 201: 14.74
+	Hs
		1025374 SPTN1_HUMAN (359-1013): 4.51e-39: 160: 11.50		CACO2_HUMAN (101-339): 6.54e-37: 140: 18.18
+	Hs
		1078923 ITSN1_HUMAN (364-1012): 1.76e-19: 96.9: 11.30		EP15R_HUMAN (78-354): 2.27e-57: 201: 14.74
+	Mm
		1141846 ITSN1_MOUSE (205-1012): 6.46e-19: 94.9: 11.81		EP15R_MOUSE (78-353): 1.02e-52: 189: 14.44
+	Hs
		1045559 SPTN1_HUMAN (359-1013): 4.51e-39: 160: 11.50		EVL_HUMAN (4-178): 9.49e-31: 122: 19.78
+	Hs
		840566 SH3G1_HUMAN (808-1013): 1.7e-29: 123: 15.02		VASP_HUMAN (4-170): 7.18e-35: 133: 23.12
+	Mm
		936832 LASP1_MOUSE (312-451): 4.09e-21: 96.2: 30.00		VASP_MOUSE (4-167): 3.42e-36: 136: 22.94
+	Hs
		840475 LASP1_HUMAN (496-672): 7.48e-19: 89.4: 25.14		VASP_HUMAN (4-170): 7.18e-35: 133: 23.12
+	Hs
		235499 VINEX_HUMAN (858-1010): 1.08e-13: 77.3: 27.45		CACO2_HUMAN (101-339): 6.54e-37: 140: 18.18
+	Ce
		104681 SRBS1_CAEEL (784-1011): 1.55e-11: 70.8: 22.51		G5EG53_CAEEL (5-187): 4.25e-38: 143: 20.21
+	Hs
		787985 ITSN2_HUMAN (412-1011): 8.62e-21: 101: 15.16		EPS15_HUMAN (78-327): 1.5e-16: 83.1: 13.31
+	Rn
		92844 ITSN1_RAT (205-1012): 1.03e-18: 94.5: 11.86		E9PSY8_RAT (78-321): 1.56e-17: 86.2: 12.50
+	Hs
		787920 ITSN1_HUMAN (364-1012): 1.76e-19: 96.9: 11.30		EPS15_HUMAN (78-327): 1.5e-16: 83.1: 13.31
+	Cl
		47357 F1PHV6_CANLF (361-1012): 2.61e-17: 89.9: 9.87		A0A8I3PJA6_CANLF (78-327): 3.07e-16: 82.3: 12.93