HitPredict

Interactor 1: RNF8 (O76064)
E3 ubiquitin-protein ligase RNF8 (hRNF8) (EC 2.3.2.27) (RING finger protein 8) (RING-type E3 ubiquitin transferase RNF8)
Gene: RNF8

Interactor 2: TRI29 (Q14134)
Tripartite motif-containing protein 29 (Ataxia telangiectasia group D-associated protein)
Gene: TRIM29

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	26381412
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 485 Hs			1 588
+	Hs
		282521 RNF8_HUMAN (1-485): 0: 523: 100.00		RO52_HUMAN (140-588): 2.7e-92: 293: 16.74
+	Hs
		537000 UHRF2_HUMAN (204-472): 7.12e-40: 155: 13.07		TRI27_HUMAN (140-503): 7.63e-79: 259: 14.42
+	Hs
		584870 RO52_HUMAN (389-483): 7.64e-26: 112: 31.25		RO52_HUMAN (140-588): 2.7e-92: 293: 16.74
+	Mm
		1112402 RO52_MOUSE (385-483): 2.42e-26: 113: 24.00		Q3U7K7_MOUSE (143-534): 4.37e-87: 279: 15.80
+	Hs
		585058 RO52_HUMAN (389-483): 7.64e-26: 112: 31.25		TRIM5_HUMAN (140-533): 1.09e-83: 271: 17.10
+	Hs
		1299584 UHRF2_HUMAN (204-472): 7.12e-40: 155: 13.07		TRIM8_HUMAN (171-531): 3.4e-66: 227: 18.43
+	Hs
		536850 LONF1_HUMAN (243-483): 1.28e-27: 118: 19.26		TRI27_HUMAN (140-503): 7.63e-79: 259: 14.42
+	Hs
		262150 RO52_HUMAN (389-483): 7.64e-26: 112: 31.25		TRIM3_HUMAN (136-566): 5.8e-77: 260: 15.75
+	Hs
		585075 RO52_HUMAN (389-483): 7.64e-26: 112: 31.25		TRI39_HUMAN (148-531): 5.93e-79: 260: 14.75
+	Hs
		536726 RO52_HUMAN (389-483): 7.64e-26: 112: 31.25		TRI27_HUMAN (140-503): 7.63e-79: 259: 14.42
+	Hs
		1223387 TRI22_HUMAN (396-484): 9.31e-25: 108: 25.25		TRI22_HUMAN (147-519): 6.8e-79: 259: 16.75
+	Hs
		536970 TRI43_HUMAN (389-485): 3.68e-24: 106: 24.00		TRI27_HUMAN (140-503): 7.63e-79: 259: 14.42
+	Hs
		1318723 TRIM4_HUMAN (393-485): 5.7e-25: 109: 23.47		TRIM4_HUMAN (143-462): 3.46e-75: 249: 11.73
+	Hs
		1089389 LONF1_HUMAN (243-483): 1.28e-27: 118: 19.26		TRIM1_HUMAN (91-432): 5.04e-65: 228: 17.42
+	Hs
		1089378 LONF1_HUMAN (243-483): 1.28e-27: 118: 19.26		TRIM8_HUMAN (171-531): 3.4e-66: 227: 18.43
+	Hs
		585056 RO52_HUMAN (389-483): 7.64e-26: 112: 31.25		TRIM8_HUMAN (171-531): 3.4e-66: 227: 18.43
+	Hs
		1285825 TRI43_HUMAN (389-485): 3.68e-24: 106: 24.00		TRIM8_HUMAN (171-531): 3.4e-66: 227: 18.43
+	Hs
		1089351 LONF1_HUMAN (243-483): 1.28e-27: 118: 19.26		TRI42_HUMAN (151-383): 7.89e-43: 165: 19.57
+	Hs
		1261095 TRIM4_HUMAN (393-485): 5.7e-25: 109: 23.47		TRI41_HUMAN (182-393): 5.56e-42: 162: 22.07