HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37689310, 23891004
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 339 Hs			1 1164
+	Hs
		1267512 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		TSC1_HUMAN (1-1164): 0: 725: 100.00
+	Hs
		282900 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		282814 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		282948 CIAO1_HUMAN (1-337): 6.29e-105: 312: 100.00		PHLB1_HUMAN (280-850): 6.61e-14: 79.1: 11.33
+	Hs
		1051392 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		792983 LIS1_HUMAN (224-339): 5.41e-16: 80.1: 15.52		DCTN1_HUMAN (540-1022): 9.26e-59: 223: 16.33
+	Hs
		1268063 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		724952 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		MYH9_HUMAN (673-1164): 1.25e-23: 111: 12.40
+	Hs
		1281519 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		MRCKB_HUMAN (835-1162): 1.41e-15: 84.5: 6.67
+	Hs
		1189782 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		MYH14_HUMAN (620-918): 1.78e-11: 71.1: 13.11
+	Hs
		725215 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43
+	Hs
		903399 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		MY18A_HUMAN (461-1064): 4e-25: 115: 10.31
+	Hs
		148610 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78
+	Hs
		551854 NLE1_HUMAN (226-339): 2.65e-18: 87.5: 14.91		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		551655 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		551766 WDR5B_HUMAN (233-339): 2.17e-17: 83.6: 14.95		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		551632 LIS1_HUMAN (224-339): 5.41e-16: 80.1: 15.52		DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54
+	Hs
		903285 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		CYTSB_HUMAN (740-1117): 1.86e-12: 74.1: 12.41
+	Hs
		903334 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		MYH14_HUMAN (620-918): 1.78e-11: 71.1: 13.11
+	Hs
		792973 LIS1_HUMAN (224-339): 5.41e-16: 80.1: 15.52		CENPE_HUMAN (620-984): 9.03e-10: 65.5: 20.36