HitPredict

Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17353931
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0008284 - positive regulation of cell population proliferation
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 488
+	Hs
		1270423 TBL1R_HUMAN (3-283): 1.27e-63: 211: 25.52		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1270358 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		1038686 TBL1R_HUMAN (3-283): 1.27e-63: 211: 25.52		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		878219 SEC13_HUMAN (28-281): 8.06e-19: 87.4: 29.64		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		903404 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		177377 TBL1R_HUMAN (3-283): 1.27e-63: 211: 25.52		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		1270370 SNR40_HUMAN (234-339): 2.57e-15: 77.8: 19.81		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		245623 TBL1X_HUMAN (58-218): 4.02e-13: 72: 26.47		HDAC2_HUMAN (1-488): 0: 707: 100.00
+	Hs
		903202 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Dm
		1182201 EBI_DROME (6-181): 5.14e-46: 167: 27.03		Q7KTS4_DROME (10-430): 0: 560: 57.11
+	Dm
		1279322 EBI_DROME (6-181): 5.14e-46: 167: 27.03		Q9VNC2_DROME (10-430): 0: 556: 56.88
+	Hs
		245600 TBL1X_HUMAN (58-218): 4.02e-13: 72: 26.47		HDAC1_HUMAN (1-443): 0: 642: 90.07
+	Hs
		177249 WDR5_HUMAN (225-339): 4.64e-18: 85.5: 15.65		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		177369 TBL1Y_HUMAN (58-218): 5.74e-14: 74.3: 28.24		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Hs
		177148 TBL1X_HUMAN (58-218): 4.02e-13: 72: 26.47		HDAC3_HUMAN (10-431): 0: 574: 58.26
+	Mm
		1157816 SEC13_MOUSE (28-281): 1.14e-19: 89.7: 29.64		HDAC4_MOUSE (1-377): 6.12e-133: 412: 23.89
+	Hs
		1260185 TBL1R_HUMAN (3-283): 1.27e-63: 211: 25.52		HDAC7_HUMAN (29-280): 1.96e-23: 106: 26.37
+	Hs
		1260173 FBXW7_HUMAN (3-217): 6.6e-46: 167: 19.73		HDAC7_HUMAN (29-280): 1.96e-23: 106: 26.37
+	Hs
		245622 TBL1X_HUMAN (58-218): 4.02e-13: 72: 26.47		HDAC7_HUMAN (29-280): 1.96e-23: 106: 26.37