Interactor 1: CIAO1 (O76071)
Probable cytosolic iron-sulfur protein assembly protein CIAO1 (WD repeat-containing protein 39)
Gene: CIAO1

Interactor 2: CIA2A (Q9H5X1)
Cytosolic iron-sulfur assembly component 2A (MIP18 family protein FAM96A)
Gene: CIAO2A

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.974

The method score is based on:

Property Details
Experiments 24981860, 33961781, 23891004, 25416956, 16189514, 32296183, unassigned1304, 32222833
Identification Methods affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, tandem affinity purification, molecular sieving, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains FeS_assembly_P~WD40
Common GO terms GO:0007059 - chromosome segregation
GO:0016226 - iron-sulfur cluster assembly
GO:0097361 - cytosolic [4Fe-4S] assembly targeting complex
GO:0097428 - protein maturation by iron-sulfur cluster transfer
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 339
Hs

1 160
+ Hs
+ Sc
+ Hs
+ Ce
+ Dm
+ Hs
+ Dm

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Last updated: 15 Jul 2024