HitPredict

Interactor 1: PDE5A (O76074)
cGMP-specific 3',5'-cyclic phosphodiesterase (EC 3.1.4.35) (cGMP-binding cGMP-specific phosphodiesterase) (CGB-PDE)
Gene: PDE5A

Interactor 2: AIPL1 (Q9NZN9)
Aryl-hydrocarbon-interacting protein-like 1
Gene: AIPL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	27173435, 33961781
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 875 Hs			1 384
+	Rn
		963099 PDE2A_RAT (129-859): 0: 714: 28.32		AIP_RAT (2-329): 1.63e-77: 244: 50.00
+	Hs
		118641 PDE2A_HUMAN (126-859): 0: 706: 28.30		AIP_HUMAN (2-329): 2.47e-78: 246: 49.39
+	Rn
		872397 PDE4A_RAT (486-871): 7.83e-143: 445: 21.40		AIP_RAT (2-329): 1.63e-77: 244: 50.00
+	Hs
		118730 PDE7A_HUMAN (551-863): 3.22e-119: 372: 27.81		AIP_HUMAN (2-329): 2.47e-78: 246: 49.39
+	Hs
		259925 PDE4A_HUMAN (486-872): 1.27e-135: 428: 21.14		FKBP6_HUMAN (3-329): 8.56e-53: 180: 15.87