HitPredict

Interactor 1: PDE9A (O76083)
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)
Gene: PDE9A

Interactor 2: PDE9A (O76083)
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A (EC 3.1.4.35)
Gene: PDE9A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.874

The method score is based on:

Property Details
Experiments 25416956, 16189514, 26871637
Identification Methods two hybrid, two hybrid array, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PDEase_I~PDEase_I
Common GO terms GO:0004114 - 3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0004115 - 3',5'-cyclic-AMP phosphodiesterase activity
GO:0005654 - nucleoplasm
GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus
and 15 others

more...
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 593
Hs

1 593
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024