HitPredict

Interactor 1: SRP72 (O76094)
Signal recognition particle subunit SRP72 (SRP72) (Signal recognition particle 72 kDa protein)
Gene: SRP72

Interactor 2: SRP68 (Q9UHB9)
Signal recognition particle subunit SRP68 (SRP68) (Signal recognition particle 68 kDa protein)
Gene: SRP68

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.708

The method score is based on:

Property	Details
Experiments	35271311, 28514442, 33961781, 16672232
Identification Methods	affinity chromatography technology, cosedimentation through density gradient, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005047 - signal recognition particle binding GO:0005783 - endoplasmic reticulum GO:0005786 - signal recognition particle, endoplasmic reticulum targeting GO:0005829 - cytosol and 3 others more... GO:0006614 - SRP-dependent cotranslational protein targeting to membrane GO:0008312 - 7S RNA binding GO:0048500 - signal recognition particle
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	671
Hs

1	627

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024