HitPredict

Interactor 1: O76216 (O76216)
Histone acetyltransferase GCN5 (EC 2.3.1.48)
Gene: Gcn5

Interactor 2: TAD2A (Q7KSD8)
Transcriptional adapter 2A (dADA2a)
Gene: Ada2a

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.786

Property	Details
Experiments	12482983, 20813260
Identification Methods	two hybrid, molecular sieving, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Acetyltransf_1~Myb_DNA-binding
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006338 - chromatin remodeling GO:0140672 - ATAC complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 813 Dm			1 562
+	Dm
		1181824 Q9VTZ1_DROME (1-813): 0: 1141: 99.63		TAD2A_DROME (1-562): 0: 668: 100.00
+	Mm
		1208540 KAT2B_MOUSE (35-813): 0: 1068: 44.82		TAD2A_MOUSE (81-557): 5.28e-143: 422: 31.41
+	Hs
		266399 KAT2B_HUMAN (71-813): 0: 1029: 47.01		TAD2A_HUMAN (81-557): 7.67e-146: 429: 30.99
+	Dm
		1212009 Q9VTZ1_DROME (1-813): 0: 1141: 99.63		TAD2B_DROME (92-441): 2.83e-96: 305: 24.52
+	Dm
		283714 O76216_DROME (1-813): 0: 1139: 100.00		TAD2B_DROME (92-441): 2.83e-96: 305: 24.52
+	Mm
		1208541 KAT2A_MOUSE (61-813): 0: 1020: 47.14		TAD2A_MOUSE (81-557): 5.28e-143: 422: 31.41
+	Hs
		266398 KAT2A_HUMAN (58-813): 0: 1012: 47.10		TAD2A_HUMAN (81-557): 7.67e-146: 429: 30.99
+	Hs
		1198566 KAT2B_HUMAN (71-813): 0: 1029: 47.01		TAD2B_HUMAN (89-560): 1.21e-136: 405: 23.57
+	Hs
		1198565 KAT2A_HUMAN (58-813): 0: 1012: 47.10		TAD2B_HUMAN (89-560): 1.21e-136: 405: 23.57
+	Sc
		970392 GCN5_YEAST (398-811): 1.71e-165: 488: 37.44		ADA2_YEAST (91-555): 1.56e-137: 407: 21.78
+	At
		1308015 GCN5_ARATH (453-806): 3.73e-149: 451: 41.76		TAD2A_ARATH (91-553): 1.63e-127: 386: 20.23
+	At
		1308007 GCN5_ARATH (453-806): 3.73e-149: 451: 41.76		TAD2B_ARATH (73-553): 4.59e-128: 385: 21.77
+	Sc
		797934 GCN5_YEAST (398-811): 1.71e-165: 488: 37.44		RSC8_YEAST (42-343): 5.86e-52: 188: 12.95
+	Pf
		1211774 Q8IB67_PLAF7 (435-808): 2.88e-137: 443: 38.42		Q8I5G5_PLAF7 (58-209): 8.72e-29: 123: 13.77
+	At
		1275616 GTE11_ARATH (623-810): 4.92e-39: 156: 21.33		SWI3C_ARATH (74-437): 7.72e-44: 168: 12.73
+	Sc
		728711 BDF1_YEAST (640-812): 2.91e-22: 104: 20.57		RSC8_YEAST (42-343): 5.86e-52: 188: 12.95
+	At
		1195144 GTE11_ARATH (623-810): 4.92e-39: 156: 21.33		SWI3B_ARATH (76-411): 4.25e-30: 125: 12.36
+	At
		1258938 GTE11_ARATH (623-810): 4.92e-39: 156: 21.33		SWI3A_ARATH (95-387): 2.17e-12: 71.5: 13.77