HitPredict

Interactor 1: O76216 (O76216)
Histone acetyltransferase GCN5 (EC 2.3.1.48)
Gene: Gcn5

Interactor 2: TAD2B (Q8I8V0)
Transcriptional adapter 2B (dADA2b)
Gene: Ada2b

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	1.00	0.770

Property	Details
Experiments	12482983, 18034162
Identification Methods	anti bait coimmunoprecipitation, two hybrid
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	Acetyltransf_1~Myb_DNA-binding
Common GO terms	GO:0000124 - SAGA complex GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005700 - polytene chromosome GO:0006338 - chromatin remodeling
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 813 Dm			1 555
+	Dm
		1212009 Q9VTZ1_DROME (1-813): 0: 1141: 99.63		TAD2B_DROME (1-555): 0: 680: 100.00
+	Hs
		1198566 KAT2B_HUMAN (71-813): 0: 1029: 47.01		TAD2B_HUMAN (4-412): 4.6e-142: 418: 36.39
+	Dm
		1181824 Q9VTZ1_DROME (1-813): 0: 1141: 99.63		TAD2A_DROME (13-367): 1.76e-92: 296: 24.35
+	Dm
		283712 O76216_DROME (1-813): 0: 1139: 100.00		TAD2A_DROME (13-367): 1.76e-92: 296: 24.35
+	Hs
		1198565 KAT2A_HUMAN (58-813): 0: 1012: 47.10		TAD2B_HUMAN (4-412): 4.6e-142: 418: 36.39
+	Mm
		1208540 KAT2B_MOUSE (35-813): 0: 1068: 44.82		TAD2A_MOUSE (6-412): 5.14e-110: 337: 23.56
+	Hs
		266399 KAT2B_HUMAN (71-813): 0: 1029: 47.01		TAD2A_HUMAN (6-412): 2.74e-111: 340: 23.56
+	Mm
		1208541 KAT2A_MOUSE (61-813): 0: 1020: 47.14		TAD2A_MOUSE (6-412): 5.14e-110: 337: 23.56
+	Hs
		266398 KAT2A_HUMAN (58-813): 0: 1012: 47.10		TAD2A_HUMAN (6-412): 2.74e-111: 340: 23.56
+	Sc
		970392 GCN5_YEAST (398-811): 1.71e-165: 488: 37.44		ADA2_YEAST (7-412): 3.3e-122: 368: 23.06
+	At
		1308007 GCN5_ARATH (453-806): 3.73e-149: 451: 41.76		TAD2B_ARATH (1-410): 3.98e-114: 349: 23.54
+	At
		1308015 GCN5_ARATH (453-806): 3.73e-149: 451: 41.76		TAD2A_ARATH (11-410): 6.47e-83: 270: 17.79
+	Sc
		797934 GCN5_YEAST (398-811): 1.71e-165: 488: 37.44		RSC8_YEAST (6-285): 2.4e-48: 178: 14.53
+	Sc
		696166 GCN5_YEAST (398-811): 1.71e-165: 488: 37.44		SWI3_YEAST (59-375): 2.6e-44: 170: 12.88
+	Pf
		1211774 Q8IB67_PLAF7 (435-808): 2.88e-137: 443: 38.42		Q8I5G5_PLAF7 (13-133): 1.52e-20: 98: 12.21
+	At
		1275616 GTE11_ARATH (623-810): 4.92e-39: 156: 21.33		SWI3C_ARATH (12-289): 9.27e-40: 156: 15.89
+	At
		1195144 GTE11_ARATH (623-810): 4.92e-39: 156: 21.33		SWI3B_ARATH (2-258): 1.42e-40: 155: 13.79
+	Hs
		998902 EP300_HUMAN (614-805): 8.16e-38: 155: 20.51		SMRC2_HUMAN (49-256): 5.79e-26: 114: 9.52
+	Hs
		998950 EP300_HUMAN (614-805): 8.16e-38: 155: 20.51		SMRC1_HUMAN (67-202): 3.5e-18: 90.7: 12.86
+	At
		1258938 GTE11_ARATH (623-810): 4.92e-39: 156: 21.33		SWI3A_ARATH (12-303): 3.02e-11: 68: 12.32