HitPredict

Interactor 1: CED6 (O76337)
Cell death protein 6 (Candidate adapter protein ced-6)
Gene: ced-6

Interactor 2: YKA7 (P34258)
Uncharacterized protein B0303.7
Gene: B0303.7

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.50	0.464

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 492 Ce			1 493
+	Ce
		283754 CED6_CAEEL (1-492): 1.64e-150: 440: 100.00		Q9U2T9_CAEEL (30-493): 7.29e-30: 126: 14.76
+	Mm
		956235 DAB1_MOUSE (31-433): 6.36e-74: 246: 17.21		NCK1_MOUSE (130-350): 3.76e-31: 125: 16.96
+	Mm
		223010 DAB1_MOUSE (31-433): 6.36e-74: 246: 17.21		NCK2_MOUSE (126-360): 4.5e-30: 122: 16.80
+	Hs
		269120 DAB1_HUMAN (31-433): 6.15e-73: 243: 16.12		NCK1_HUMAN (130-350): 6.22e-31: 125: 17.83
+	Hs
		208964 DAB1_HUMAN (31-433): 6.15e-73: 243: 16.12		NCK2_HUMAN (126-351): 3.85e-29: 120: 18.72
+	Hs
		557659 DAB2_HUMAN (13-435): 6.15e-67: 231: 17.58		NCK1_HUMAN (130-350): 6.22e-31: 125: 17.83
+	Mm
		957157 DAB2_MOUSE (13-435): 1.01e-65: 227: 17.58		ITSN1_MOUSE (3-357): 1.55e-30: 128: 15.51
+	Rn
		924995 SHC1_RAT (11-402): 1.36e-87: 278: 18.87		GRB2_RAT (434-492): 7.92e-13: 69.5: 28.33
+	Hs
		269148 DAB1_HUMAN (31-433): 6.15e-73: 243: 16.12		ITSN1_HUMAN (27-493): 1.28e-20: 98: 14.14
+	Hs
		957186 DAB2_HUMAN (13-435): 6.15e-67: 231: 17.58		ITSN1_HUMAN (27-493): 1.28e-20: 98: 14.14
+	Mm
		957235 SHC1_MOUSE (11-402): 1.14e-77: 255: 18.63		GRB2_MOUSE (434-492): 7.92e-13: 69.5: 28.33
+	Hs
		666104 SHC1_HUMAN (11-402): 4.06e-73: 243: 18.03		GRAP_HUMAN (197-413): 5.81e-16: 78.8: 16.29
+	Hs
		269176 DAB1_HUMAN (31-433): 6.15e-73: 243: 16.12		SH3K1_HUMAN (360-493): 5.24e-14: 76.5: 18.47
+	Hs
		666057 SHC1_HUMAN (11-402): 4.06e-73: 243: 18.03		GRB2_HUMAN (434-492): 7.92e-13: 69.5: 28.33
+	Hs
		924476 SHC2_HUMAN (21-402): 4.56e-73: 243: 15.65		GRB2_HUMAN (434-492): 7.92e-13: 69.5: 28.33
+	Hs
		957207 DAB2_HUMAN (13-435): 6.15e-67: 231: 17.58		SH3K1_HUMAN (360-493): 5.24e-14: 76.5: 18.47
+	Mm
		957150 DAB2_MOUSE (13-435): 1.01e-65: 227: 17.58		SH3K1_MOUSE (360-493): 8.89e-14: 76.1: 19.11
+	Hs
		924477 DAB2_HUMAN (13-435): 6.15e-67: 231: 17.58		GRB2_HUMAN (434-492): 7.92e-13: 69.5: 28.33
+	Hs
		924646 SHC4_HUMAN (8-402): 1.66e-67: 229: 14.93		GRB2_HUMAN (434-492): 7.92e-13: 69.5: 28.33
+	Mm
		957139 DAB2_MOUSE (13-435): 1.01e-65: 227: 17.58		GRB2_MOUSE (434-492): 7.92e-13: 69.5: 28.33