HitPredict

Interactor 1: CED6 (O76337)
Cell death protein 6 (Candidate adapter protein ced-6)
Gene: ced-6

Interactor 2: Q9N4F3 (Q9N4F3)
AP complex subunit beta
Gene: apb-1

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	23696751
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 492 Ce			1 955
+	Hs
		833572 NUMB_HUMAN (28-451): 1.01e-73: 246: 18.54		AP2B1_HUMAN (1-954): 0: 857: 62.79
+	Hs
		666058 SHC1_HUMAN (11-402): 4.06e-73: 243: 18.03		AP2B1_HUMAN (1-954): 0: 857: 62.79
+	Hs
		926067 NUMBL_HUMAN (11-431): 2.49e-72: 242: 17.08		AP2B1_HUMAN (1-954): 0: 857: 62.79
+	Hs
		833587 NUMB_HUMAN (28-451): 1.01e-73: 246: 18.54		AP1B1_HUMAN (1-954): 0: 851: 62.75
+	Hs
		666090 SHC1_HUMAN (11-402): 4.06e-73: 243: 18.03		AP1B1_HUMAN (1-954): 0: 851: 62.75
+	Hs
		957123 SHC2_HUMAN (21-402): 4.56e-73: 243: 15.65		AP1B1_HUMAN (1-954): 0: 851: 62.75
+	Hs
		925851 DAB2_HUMAN (13-435): 6.15e-67: 231: 17.58		AP2B1_HUMAN (1-954): 0: 857: 62.79
+	Rn
		923852 Q3MUI1_RAT (28-385): 4.97e-59: 206: 20.15		AP2B1_RAT (1-954): 0: 857: 62.79
+	Ce
		283751 CED6_CAEEL (1-492): 1.64e-150: 440: 100.00		Q22601_CAEEL (14-562): 3.82e-141: 446: 20.23
+	Hs
		321513 NUMB_HUMAN (28-451): 1.01e-73: 246: 18.54		AP2A1_HUMAN (11-954): 0: 639: 16.22
+	Hs
		321492 SHC1_HUMAN (11-402): 4.06e-73: 243: 18.03		AP2A1_HUMAN (11-954): 0: 639: 16.22
+	Hs
		321527 SHC2_HUMAN (21-402): 4.56e-73: 243: 15.65		AP2A1_HUMAN (11-954): 0: 639: 16.22
+	Hs
		321528 DAB2_HUMAN (13-435): 6.15e-67: 231: 17.58		AP2A1_HUMAN (11-954): 0: 639: 16.22
+	Hs
		302120 NUMB_HUMAN (28-451): 1.01e-73: 246: 18.54		AP2A2_HUMAN (12-954): 0: 594: 14.83
+	Hs
		302103 SHC1_HUMAN (11-402): 4.06e-73: 243: 18.03		AP2A2_HUMAN (12-954): 0: 594: 14.83
+	Hs
		302137 DAB2_HUMAN (13-435): 6.15e-67: 231: 17.58		AP2A2_HUMAN (12-954): 0: 594: 14.83
+	Rn
		577194 Q3MUI1_RAT (28-385): 4.97e-59: 206: 20.15		AP2A2_RAT (11-954): 0: 608: 16.06
+	Rn
		1109842 Q3MUI1_RAT (28-385): 4.97e-59: 206: 20.15		Q66HM2_RAT (11-954): 0: 604: 15.95
+	Dm
		561275 NUMB_DROME (11-434): 1.52e-64: 220: 18.08		AP2A_DROME (11-954): 0: 566: 14.16
+	Dm
		561280 NUMB_DROME (11-434): 1.52e-64: 220: 18.08		Q7KVR8_DROME (14-811): 1.68e-155: 485: 16.55