HitPredict

Interactor 1: CED6 (O76337)
Cell death protein 6 (Candidate adapter protein ced-6)
Gene: ced-6

Interactor 2: Q9U2T9 (Q9U2T9)
Intersectin-1
Gene: itsn-1

Species: Caenorhabditis elegans

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.59	0.50	0.543

Property	Details
Experiments	18298590, 23549480
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 492 Ce			1 1085
+	Ce
		283748 CED6_CAEEL (1-492): 1.64e-150: 440: 100.00		YKA7_CAEEL (665-936): 1.1e-19: 95.9: 16.61
+	Hs
		833668 NUMB_HUMAN (28-451): 1.01e-73: 246: 18.54		EP15R_HUMAN (5-473): 6.97e-71: 256: 22.69
+	Hs
		787868 NUMB_HUMAN (28-451): 1.01e-73: 246: 18.54		EPS15_HUMAN (4-576): 1.54e-61: 229: 18.12
+	Mm
		788008 NUMB_MOUSE (28-451): 3.67e-77: 256: 18.96		EPS15_MOUSE (4-464): 1.55e-54: 208: 20.78
+	Hs
		787894 DAB2_HUMAN (13-435): 6.15e-67: 231: 17.58		EPS15_HUMAN (4-576): 1.54e-61: 229: 18.12
+	Mm
		787999 DAB2_MOUSE (13-435): 1.01e-65: 227: 17.58		EPS15_MOUSE (4-464): 1.55e-54: 208: 20.78
+	Hs
		269120 DAB1_HUMAN (31-433): 6.15e-73: 243: 16.12		NCK1_HUMAN (887-1082): 7.16e-35: 139: 22.27
+	Hs
		557659 DAB2_HUMAN (13-435): 6.15e-67: 231: 17.58		NCK1_HUMAN (887-1082): 7.16e-35: 139: 22.27
+	Mm
		223010 DAB1_MOUSE (31-433): 6.36e-74: 246: 17.21		NCK2_MOUSE (660-958): 2.72e-26: 114: 19.47
+	Hs
		208964 DAB1_HUMAN (31-433): 6.15e-73: 243: 16.12		NCK2_HUMAN (660-960): 3.34e-25: 110: 18.69
+	Rn
		924995 SHC1_RAT (11-402): 1.36e-87: 278: 18.87		GRB2_RAT (1030-1085): 4.24e-13: 71.7: 33.33
+	Mm
		957235 SHC1_MOUSE (11-402): 1.14e-77: 255: 18.63		GRB2_MOUSE (1030-1085): 5.12e-13: 71.3: 33.33
+	Hs
		269148 DAB1_HUMAN (31-433): 6.15e-73: 243: 16.12		ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35
+	Hs
		666186 SHC1_HUMAN (11-402): 4.06e-73: 243: 18.03		VAV3_HUMAN (875-1084): 4.84e-15: 82.1: 18.11
+	Mm
		956235 DAB1_MOUSE (31-433): 6.36e-74: 246: 17.21		NCK1_MOUSE (963-1085): 5.57e-14: 77.1: 21.82
+	Hs
		666057 SHC1_HUMAN (11-402): 4.06e-73: 243: 18.03		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		924476 SHC2_HUMAN (21-402): 4.56e-73: 243: 15.65		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		957186 DAB2_HUMAN (13-435): 6.15e-67: 231: 17.58		ITSN1_HUMAN (780-940): 3.98e-15: 82.9: 26.35
+	Hs
		924477 DAB2_HUMAN (13-435): 6.15e-67: 231: 17.58		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33
+	Hs
		924646 SHC4_HUMAN (8-402): 1.66e-67: 229: 14.93		GRB2_HUMAN (1030-1085): 4.24e-13: 71.7: 33.33