Interactor 1: O76417 (O76417)
MutL homolog PMS2
Gene: Pms2

Interactor 2: Q8T0N1 (Q8T0N1)
GH18717p
Gene: Mlh1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.34 1.00 0.590

The method score is based on:

Property Details
Experiments 15710747
Identification Methods two hybrid fragment pooling approach
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_mis_repair~HATPase_c_3, Mlh1_C~MutL_C
Common GO terms GO:0005524 - ATP binding
GO:0006298 - mismatch repair
GO:0016446 - somatic hypermutation of immunoglobulin genes
GO:0016887 - ATP hydrolysis activity
GO:0030983 - mismatched DNA binding
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 893
Dm

1 504
+ Dm
+ Hs
+ Hs
+ Sc
+ Ce
+ Sc
+ Sc
+ Sc
+ Hs
+ Sc
+ Hs
+ Ec
+ Sc

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Last updated: 15 Jul 2024