Interactor 1: UBP2 (O75604)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Gene: USP2

Interactor 2: UBP54 (Q70EL1)
Ubiquitin carboxyl-terminal hydrolase 54 (EC 3.4.19.12) (Ubiquitin-specific peptidase 54)
Gene: USP54

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 0.90 0.742

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~UCH
Common GO terms GO:0004843 - cysteine-type deubiquitinase activity
GO:0006508 - proteolysis
GO:0016579 - protein deubiquitination
Homologous interactions 0

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Last updated: 11Aug2025