Interactor 1: LY86 (O88188)
Lymphocyte antigen 86 (Ly-86) (Protein MD-1)
Gene: LY86

Interactor 2: CD180 (Q62192)
CD180 antigen (Lymphocyte antigen 78) (Ly-78) (Radioprotective 105 kDa protein) (CD antigen CD180)
Gene: CD180

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.893

The method score is based on:

Property Details
Experiments 21857663, 19154986, 21959264, 9686597
Identification Methods pull down, molecular sieving, anti tag coimmunoprecipitation, x-ray crystallography, coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains E1_DerP2_DerF2~LRR_8
Common GO terms GO:0006954 - inflammatory response
GO:0031663 - lipopolysaccharide-mediated signaling pathway
GO:0031666 - positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0045087 - innate immune response
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 162
Mm

1 661
+ Hs
+ Hs
+ Bt

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024