HitPredict

Interactor 1: WIZ (O88286)
Protein Wiz (Widely-interspaced zinc finger-containing protein)
Gene: WIZ

Interactor 2: NANOG (Q80Z64)
Homeobox protein NANOG (ES cell-associated protein 4) (Early embryo specific expression NK-type homeobox protein) (Homeobox transcription factor Nanog)
Gene: NANOG

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23892456
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1684 Mm			1 305
+	Hs
		321714 WIZ_HUMAN (1-1670): 0: 1379: 80.69		TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80
+	Hs
		321734 WIZ_HUMAN (1-1670): 0: 1379: 80.69		LHX2_HUMAN (8-232): 1.48e-30: 120: 15.49
+	Hs
		321710 WIZ_HUMAN (1-1670): 0: 1379: 80.69		PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69
+	Hs
		321728 WIZ_HUMAN (1-1670): 0: 1379: 80.69		LHX1_HUMAN (44-298): 6.25e-30: 118: 13.64
+	Hs
		213289 WIZ_HUMAN (1-1670): 0: 1379: 80.69		TLX2_HUMAN (60-158): 3.78e-27: 108: 30.39
+	Hs
		211779 WIZ_HUMAN (1-1670): 0: 1379: 80.69		TLX3_HUMAN (89-153): 9.32e-09: 57.4: 43.08
+	Hs
		620204 ZN644_HUMAN (729-848): 4.16e-45: 181: 40.95		PAX7_HUMAN (79-299): 1.61e-33: 130: 16.81
+	Hs
		679171 ZN644_HUMAN (729-848): 4.16e-45: 181: 40.95		TLX1_HUMAN (29-215): 3.58e-34: 128: 22.80
+	Hs
		839825 ZN644_HUMAN (729-848): 4.16e-45: 181: 40.95		LHX2_HUMAN (8-232): 1.48e-30: 120: 15.49
+	Hs
		641563 ZN644_HUMAN (729-848): 4.16e-45: 181: 40.95		PAX6_HUMAN (37-288): 5.3e-30: 119: 15.69
+	Hs
		822679 ZN644_HUMAN (729-848): 4.16e-45: 181: 40.95		LHX1_HUMAN (44-298): 6.25e-30: 118: 13.64
+	Hs
		213383 ZN644_HUMAN (729-848): 4.16e-45: 181: 40.95		TLX2_HUMAN (60-158): 3.78e-27: 108: 30.39
+	Mm
		100190 F6ZBR8_MOUSE (1112-1476): 4.15e-17: 89.9: 27.70		NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00
+	Hs
		1077276 ZN300_HUMAN (373-505): 8.77e-36: 147: 12.37		ALX1_HUMAN (47-294): 2.61e-35: 131: 15.73
+	Hs
		822633 OZF_HUMAN (278-418): 9.86e-38: 146: 18.24		LHX1_HUMAN (44-298): 6.25e-30: 118: 13.64
+	Mm
		1113226 ZSC10_MOUSE (296-507): 7.28e-09: 62.8: 21.82		NANOG_MOUSE (1-305): 9.78e-60: 194: 100.00
+	Hs
		211965 ZN644_HUMAN (729-848): 4.16e-45: 181: 40.95		TLX3_HUMAN (89-153): 9.32e-09: 57.4: 43.08
+	Dm
		1096920 PARIS_DROME (284-477): 8.97e-12: 70.5: 21.58		BARH1_DROME (95-153): 2e-09: 60.1: 52.54
+	Dm
		611851 PARIS_DROME (284-477): 8.97e-12: 70.5: 21.58		BAGP_DROME (93-158): 8.14e-09: 58.2: 46.97
+	Hs
		211812 ZNF41_HUMAN (304-505): 4.84e-10: 66.7: 23.38		TLX3_HUMAN (89-153): 9.32e-09: 57.4: 43.08