Interactor 1: SORL (O88307)
Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA)
Gene: Sorl1

Interactor 2: NTRK2 (P15209)
BDNF/NT-3 growth factors receptor (EC 2.7.10.1) (GP145-TrkB/GP95-TrkB) (Trk-B) (Neurotrophic tyrosine kinase receptor type 2) (TrkB tyrosine kinase)
Gene: NTRK2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 32601248
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~fn3, PK_Tyr_Ser-Thr~fn3
Common GO terms GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005886 - plasma membrane
GO:0009986 - cell surface
GO:0031901 - early endosome membrane
and 3 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 2215
Mm

1 821
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Rn
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024