Interactor 1: SORL (O88307)
Sortilin-related receptor (Gp250) (Low-density lipoprotein receptor relative with 11 ligand-binding repeats) (LDLR relative with 11 ligand-binding repeats) (LR11) (SorLA-1) (Sorting protein-related receptor containing LDLR class A repeats) (mSorLA)
Gene: Sorl1

Interactor 2: EGFR (Q01279)
Epidermal growth factor receptor (EC 2.7.10.1)
Gene: EGFR

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 32601248
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Furin-like~fn3, PK_Tyr_Ser-Thr~fn3, Recep_L_domain~fn3
Common GO terms GO:0000139 - Golgi membrane
GO:0004888 - transmembrane signaling receptor activity
GO:0005768 - endosome
GO:0005789 - endoplasmic reticulum membrane
GO:0005886 - plasma membrane
and 4 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 2215
Mm

1 1210
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+ Rn

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Last updated: 15 Jul 2024