HitPredict

Interactor 1: EPN1 (O88339)
Epsin-1 (EPS-15-interacting protein 1)
Gene: EPN1

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	14657369, 19536136, 22871113
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 575 Rn			1 810
+	Dm
		477525 Q7KU90_DROME (1-563): 8.23e-50: 186: 31.30		UBIQP_DROME (77-801): 0: 887: 97.38
+	Hs
		476657 EPN1_HUMAN (1-575): 2e-90: 291: 94.44		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		476358 EPN3_HUMAN (1-571): 8.98e-53: 192: 39.84		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		307500 EPN2_HUMAN (1-565): 9.06e-52: 189: 35.27		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		475943 OTOG_HUMAN (156-525): 3.31e-12: 72: 14.32		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		302245 SC31A_HUMAN (136-472): 7.77e-09: 60.8: 10.88		UBC_HUMAN (1-533): 0: 662: 99.81
+	Sc
		477505 ENT1_YEAST (3-225): 5.58e-63: 215: 37.22		UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73
+	Sc
		477449 ENT2_YEAST (3-528): 7.66e-59: 208: 17.67		UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73
+	Dm
		1182371 Q7KU90_DROME (1-563): 8.23e-50: 186: 31.30		R9PY16_DROME (533-801): 8.04e-100: 313: 85.50
+	At
		1091714 EPN2_ARATH (2-573): 5.3e-39: 154: 19.69		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Hs
		111209 I6L9I8_HUMAN (1-291): 1.57e-93: 291: 52.35		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		924231 EPN1_HUMAN (1-575): 2e-90: 291: 94.44		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Mm
		476869 EPN1_MOUSE (1-575): 4.06e-91: 293: 99.13		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	At
		1092229 SC24C_ARATH (270-561): 4.51e-11: 68.2: 21.68		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Hs
		397968 EPN4_HUMAN (3-560): 2.7e-80: 266: 25.43		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69
+	Mm
		476910 EPN2_MOUSE (1-571): 1.17e-61: 215: 42.69		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		924159 EPN3_HUMAN (1-571): 8.98e-53: 192: 39.84		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		307522 EPN2_HUMAN (1-565): 9.06e-52: 189: 35.27		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Hs
		475183 EPN3_HUMAN (1-571): 8.98e-53: 192: 39.84		UBB_HUMAN (1-77): 1.17e-26: 110: 98.70