Interactor 1: IKKB (O88351)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: Ikbkb

Interactor 2: CASP8 (O89110)
Caspase-8 (CASP-8) (EC 3.4.22.61) [Cleaved into: Caspase-8 subunit p18; Caspase-8 subunit p10]
Gene: CASP8

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 17213198
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DED~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0044877 - protein-containing complex binding
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 757
Mm

1 480
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

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Last updated: 15 Jul 2024