HitPredict

Interactor 1: IKKB (O88351)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: Ikbkb

Interactor 2: TNR1A (P25118)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a)
Gene: Tnfrsf1a

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.676

The method score is based on:

Property Details
Experiments 29891719, 16547522, 10795740, 19150425
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0033209 - tumor necrosis factor-mediated signaling pathway
GO:0044877 - protein-containing complex binding
GO:0045121 - membrane raft
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 757
Mm

1 454
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024