HitPredict

Interactor 1: IKKB (O88351)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: Ikbkb

Interactor 2: TNR4 (P47741)
Tumor necrosis factor receptor superfamily member 4 (OX40 antigen) (OX40L receptor) (CD antigen CD134)
Gene: Tnfrsf4

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	21282629
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 757 Mm			1 272
+	Mm
		291437 IKKB_MOUSE (1-757): 0: 699: 100.00		TNR1A_MOUSE (8-241): 5.1e-33: 127: 22.41
+	Hs
		158391 IKKB_HUMAN (1-755): 0: 683: 92.05		TNR1A_HUMAN (8-253): 3.98e-37: 138: 18.97
+	Hs
		158372 IKKB_HUMAN (1-755): 0: 683: 92.05		TNR16_HUMAN (27-240): 1.2e-36: 136: 22.40
+	Mm
		291439 IKKB_MOUSE (1-757): 0: 699: 100.00		TNR5_MOUSE (10-174): 3.07e-29: 113: 27.13
+	Hs
		158417 IKKB_HUMAN (1-755): 0: 683: 92.05		TNR3_HUMAN (15-173): 5.62e-30: 118: 26.49
+	Hs
		158399 IKKB_HUMAN (1-755): 0: 683: 92.05		TNR5_HUMAN (10-173): 9.09e-28: 109: 26.20
+	Mm
		812912 IKKA_MOUSE (1-742): 4.58e-173: 516: 48.87		TNR4_MOUSE (1-272): 8.53e-66: 208: 100.00
+	Hs
		167470 IKKA_HUMAN (1-742): 6.55e-177: 527: 49.27		TNR1B_HUMAN (3-233): 9.27e-38: 139: 22.85
+	Hs
		167467 IKKA_HUMAN (1-742): 6.55e-177: 527: 49.27		TNR1A_HUMAN (8-253): 3.98e-37: 138: 18.97
+	Hs
		167447 IKKA_HUMAN (1-742): 6.55e-177: 527: 49.27		TNR16_HUMAN (27-240): 1.2e-36: 136: 22.40
+	Hs
		167489 IKKA_HUMAN (1-742): 6.55e-177: 527: 49.27		TNR3_HUMAN (15-173): 5.62e-30: 118: 26.49
+	Mm
		626859 IKKA_MOUSE (1-742): 4.58e-173: 516: 48.87		TNR1A_MOUSE (8-241): 5.1e-33: 127: 22.41
+	Hs
		167474 IKKA_HUMAN (1-742): 6.55e-177: 527: 49.27		TNR5_HUMAN (10-173): 9.09e-28: 109: 26.20
+	Mm
		648957 IKKA_MOUSE (1-742): 4.58e-173: 516: 48.87		TNR5_MOUSE (10-174): 3.07e-29: 113: 27.13
+	Hs
		632369 M3K5_HUMAN (14-728): 1.04e-136: 438: 19.44		TNR6_HUMAN (13-140): 2.76e-29: 114: 27.61
+	Hs
		584494 TBK1_HUMAN (15-407): 2.11e-105: 340: 26.23		TNR1A_HUMAN (8-253): 3.98e-37: 138: 18.97
+	Hs
		584404 IKKE_HUMAN (15-382): 5.99e-104: 336: 27.75		TNR1A_HUMAN (8-253): 3.98e-37: 138: 18.97