HitPredict

Interactor 1: MAGI2 (O88382)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Synaptic-scaffolding molecule) (S-SCAM)
Gene: MAGI2

Interactor 2: DLGP3 (P97838)
Disks large-associated protein 3 (DAP-3) (PSD-95/SAP90-binding protein 3) (SAP90/PSD-95-associated protein 3) (SAPAP3)
Gene: Dlgap3

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	9694864
Identification Methods	filter binding
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0045202 - synapse GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1277 Rn			1 977
+	Rn
		291497 MAGI2_RAT (1-1277): 0: 758: 100.00		DLGP2_RAT (1-977): 0: 1087: 45.30
+	Rn
		291496 MAGI2_RAT (1-1277): 0: 758: 100.00		DLGP1_RAT (1-977): 0: 1053: 37.55
+	Rn
		291499 MAGI2_RAT (1-1277): 0: 758: 100.00		DLGP4_RAT (1-977): 0: 867: 35.19
+	Hs
		327239 DLG2_HUMAN (1128-1271): 1.03e-20: 100: 22.67		DLGP3_HUMAN (1-977): 0: 1241: 94.49
+	Rn
		677777 DLG4_RAT (14-322): 3.2e-20: 99: 13.31		DLGP3_RAT (1-977): 0: 1238: 100.00
+	Hs
		145949 DLG2_HUMAN (1128-1271): 1.03e-20: 100: 22.67		DLGP1_HUMAN (1-977): 0: 1086: 38.36
+	Rn
		677776 DLG4_RAT (14-322): 3.2e-20: 99: 13.31		DLGP2_RAT (1-977): 0: 1087: 45.30
+	Hs
		145947 DLG1_HUMAN (390-675): 1.16e-18: 94.2: 18.58		DLGP1_HUMAN (1-977): 0: 1086: 38.36
+	Hs
		1077291 DLG2_HUMAN (1128-1271): 1.03e-20: 100: 22.67		DLGP2_HUMAN (1-977): 0: 1076: 45.57
+	Hs
		145945 DLG4_HUMAN (370-511): 5.8e-17: 88.5: 26.17		DLGP1_HUMAN (1-977): 0: 1086: 38.36
+	Hs
		1021580 DLG1_HUMAN (390-675): 1.16e-18: 94.2: 18.58		DLGP2_HUMAN (1-977): 0: 1076: 45.57
+	Hs
		4617 DLG1_HUMAN (390-675): 1.16e-18: 94.2: 18.58		A0A1B0GTN4_HUMAN (1-977): 0: 1076: 45.57
+	Mm
		1265187 DLG2_MOUSE (1128-1271): 4.9e-21: 102: 22.67		DLGP1_MOUSE (1-977): 0: 1053: 37.55
+	Rn
		956992 DLG2_RAT (1128-1271): 4.34e-21: 102: 22.67		DLGP1_RAT (1-977): 0: 1053: 37.55
+	Rn
		677775 DLG4_RAT (14-322): 3.2e-20: 99: 13.31		DLGP1_RAT (1-977): 0: 1053: 37.55
+	Rn
		956987 GRIP1_RAT (887-1248): 7.87e-18: 91.7: 14.91		DLGP1_RAT (1-977): 0: 1053: 37.55
+	Hs
		1136441 MAGI3_HUMAN (12-800): 1.58e-28: 127: 10.55		DLGP4_HUMAN (1-977): 0: 886: 35.53
+	Hs
		1021594 DLG1_HUMAN (390-675): 1.16e-18: 94.2: 18.58		DLGP4_HUMAN (1-977): 0: 886: 35.53
+	Rn
		677778 DLG4_RAT (14-322): 3.2e-20: 99: 13.31		DLGP4_RAT (1-977): 0: 867: 35.19
+	Hs
		1077280 DLG2_HUMAN (1128-1271): 1.03e-20: 100: 22.67		Q6IS01_HUMAN (1-539): 0: 623: 36.26