HitPredict

Interactor 1: MAGI2 (O88382)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (Atrophin-1-interacting protein 1) (AIP-1) (Membrane-associated guanylate kinase inverted 2) (MAGI-2) (Synaptic-scaffolding molecule) (S-SCAM)
Gene: MAGI2

Interactor 2: NMDE1 (Q00959)
Glutamate receptor ionotropic, NMDA 2A (GluN2A) (Glutamate [NMDA] receptor subunit epsilon-1) (N-methyl D-aspartate receptor subtype 2A) (NMDAR2A) (NR2A)
Gene: Grin2a

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	9694864
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0014069 - postsynaptic density GO:0044877 - protein-containing complex binding GO:0045202 - synapse and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1277 Rn			1 1464
+	Mm
		723540 GRIP1_MOUSE (742-1268): 1.73e-32: 139: 14.43		NMDE1_MOUSE (1-1464): 0: 1775: 98.70
+	Rn
		962657 DLG2_RAT (1128-1271): 4.34e-21: 102: 22.67		NMDE1_RAT (1-1464): 0: 1774: 100.00
+	Rn
		677780 DLG4_RAT (14-322): 3.2e-20: 99: 13.31		NMDE1_RAT (1-1464): 0: 1774: 100.00
+	Hs
		1018896 DLG2_HUMAN (1128-1271): 1.03e-20: 100: 22.67		NMDE1_HUMAN (1-1464): 0: 1692: 95.22
+	Hs
		1028139 SCRIB_HUMAN (121-1071): 6.35e-43: 174: 12.74		NMDE2_HUMAN (4-1464): 0: 1503: 52.65
+	Hs
		1028142 MAGI3_HUMAN (12-800): 1.58e-28: 127: 10.55		NMDE2_HUMAN (4-1464): 0: 1503: 52.65
+	Rn
		962666 DLG2_RAT (1128-1271): 4.34e-21: 102: 22.67		NMDE2_RAT (4-1464): 0: 1522: 52.85
+	Rn
		677781 DLG4_RAT (14-322): 3.2e-20: 99: 13.31		NMDE2_RAT (4-1464): 0: 1522: 52.85
+	Mm
		963769 DLG2_MOUSE (1128-1271): 4.9e-21: 102: 22.67		NMDE2_MOUSE (4-1464): 0: 1514: 52.72
+	Hs
		1028140 DLG2_HUMAN (1128-1271): 1.03e-20: 100: 22.67		NMDE2_HUMAN (4-1464): 0: 1503: 52.65
+	Rn
		291501 MAGI2_RAT (1-1277): 0: 758: 100.00		NMDE3_RAT (9-941): 0: 804: 54.30
+	Rn
		291493 MAGI2_RAT (1-1277): 0: 758: 100.00		NMDZ1_RAT (8-940): 0: 680: 23.16
+	Rn
		677766 DLG4_RAT (14-322): 3.2e-20: 99: 13.31		GRIK2_RAT (12-919): 0: 707: 19.09
+	Mm
		621022 GRIP1_MOUSE (742-1268): 1.73e-32: 139: 14.43		GRIA2_MOUSE (11-870): 0: 657: 17.71
+	Mm
		620904 DLG2_MOUSE (1128-1271): 4.9e-21: 102: 22.67		GRIA1_MOUSE (13-912): 0: 693: 19.50
+	Rn
		585138 DLG4_RAT (14-322): 3.2e-20: 99: 13.31		GRIA1_RAT (13-912): 0: 695: 19.50
+	Mm
		723606 DLG2_MOUSE (1128-1271): 4.9e-21: 102: 22.67		NMDZ1_MOUSE (8-940): 0: 678: 23.05
+	Rn
		677765 DLG4_RAT (14-322): 3.2e-20: 99: 13.31		NMDZ1_RAT (8-940): 0: 680: 23.16
+	Rn
		585198 GRIP2_RAT (899-1274): 2.52e-20: 99.8: 13.76		GRIA3_RAT (11-870): 0: 676: 18.50
+	Rn
		585187 GRIP2_RAT (899-1274): 2.52e-20: 99.8: 13.76		GRIA2_RAT (11-870): 0: 658: 17.71