HitPredict

Interactor 1: CXCR3 (O88410)
C-X-C chemokine receptor type 3 (CXC-R3) (CXCR-3) (Interferon-inducible protein 10 receptor) (IP-10 receptor) (CD antigen CD183)
Gene: CXCR3

Interactor 2: CXCL9 (P18340)
C-X-C motif chemokine 9 (Gamma-interferon-induced monokine) (Monokine induced by interferon-gamma) (MIG) (MuMIG) (Protein m119) (Small-inducible cytokine B9)
Gene: CXCL9

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	10556837
Identification Methods	competition binding
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~IL8
Common GO terms	GO:0006954 - inflammatory response GO:0009897 - external side of plasma membrane GO:0051281 - positive regulation of release of sequestered calcium ion into cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 367 Mm			1 126
+	Hs
		625736 CXCR1_HUMAN (20-350): 3.76e-84: 260: 37.65		CXCL5_HUMAN (16-95): 2.23e-26: 96.8: 33.75
+	Mm
		291524 CXCR3_MOUSE (1-367): 1.67e-79: 249: 100.00		CXL10_MOUSE (1-95): 5.43e-30: 105: 33.33
+	Hs
		364107 CCR3_HUMAN (42-360): 7.21e-82: 255: 34.05		CXL10_HUMAN (1-95): 5.33e-27: 97.5: 35.42
+	Hs
		625737 CXCR1_HUMAN (20-350): 3.76e-84: 260: 37.65		CXCL6_HUMAN (17-95): 5.69e-24: 90.6: 30.38
+	Hs
		150319 CCR3_HUMAN (42-360): 7.21e-82: 255: 34.05		CXL11_HUMAN (1-93): 1.46e-25: 94.1: 28.72
+	Hs
		625748 CXCR2_HUMAN (25-360): 8.27e-81: 252: 39.59		CXCL5_HUMAN (16-95): 2.23e-26: 96.8: 33.75
+	Hs
		217747 CXCR5_HUMAN (31-365): 8.26e-86: 266: 38.08		CXL13_HUMAN (25-93): 6.15e-21: 82.5: 24.64
+	Hs
		486184 CXCR1_HUMAN (20-350): 3.76e-84: 260: 37.65		IL8_HUMAN (25-91): 2.92e-23: 88.3: 34.33
+	Hs
		364041 CXCR1_HUMAN (20-350): 3.76e-84: 260: 37.65		CXCL7_HUMAN (24-91): 3.48e-22: 86.4: 38.24
+	Hs
		448987 CXCR1_HUMAN (20-350): 3.76e-84: 260: 37.65		GROA_HUMAN (24-91): 3.45e-22: 85.6: 41.18
+	Hs
		625758 CXCR2_HUMAN (25-360): 8.27e-81: 252: 39.59		CXCL6_HUMAN (17-95): 5.69e-24: 90.6: 30.38
+	Hs
		587786 CXCR2_HUMAN (25-360): 8.27e-81: 252: 39.59		CXCL3_HUMAN (24-93): 6.87e-24: 90.2: 41.43
+	Hs
		849615 CCR3_HUMAN (42-360): 7.21e-82: 255: 34.05		CXCL9_HUMAN (20-121): 1.62e-22: 87.1: 67.65
+	Hs
		486185 CXCR2_HUMAN (25-360): 8.27e-81: 252: 39.59		IL8_HUMAN (25-91): 2.92e-23: 88.3: 34.33
+	Hs
		587767 CXCR2_HUMAN (25-360): 8.27e-81: 252: 39.59		CXCL2_HUMAN (19-92): 3.26e-23: 88.3: 40.54
+	Hs
		364042 CXCR2_HUMAN (25-360): 8.27e-81: 252: 39.59		CXCL7_HUMAN (24-91): 3.48e-22: 86.4: 38.24
+	Hs
		448988 CXCR2_HUMAN (25-360): 8.27e-81: 252: 39.59		GROA_HUMAN (24-91): 3.45e-22: 85.6: 41.18
+	Hs
		150317 CXCR3_HUMAN (1-367): 8.04e-77: 242: 86.41		CXL11_HUMAN (1-93): 1.46e-25: 94.1: 28.72
+	Hs
		217751 CXCR3_HUMAN (1-367): 8.04e-77: 242: 86.41		CXL13_HUMAN (25-93): 6.15e-21: 82.5: 24.64
+	Hs
		364080 CXCR3_HUMAN (1-367): 8.04e-77: 242: 86.41		PLF4_HUMAN (27-91): 7.76e-20: 79.4: 29.23