HitPredict

Interactor 1: DC1I1 (O88485)
Cytoplasmic dynein 1 intermediate chain 1 (Cytoplasmic dynein intermediate chain 1) (Dynein intermediate chain 1, cytosolic) (DH IC-1)
Gene: Dync1i1

Interactor 2: DYL1 (P63168)
Dynein light chain 1, cytoplasmic (8 kDa dynein light chain) (DLC8) (Dynein light chain LC8-type 1) (Protein inhibitor of neuronal nitric oxide synthase) (PIN) (mPIN)
Gene: Dynll1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16946704
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Dynein_IC2~Dynein_light
Common GO terms	GO:0000776 - kinetochore GO:0005868 - cytoplasmic dynein complex GO:0005874 - microtubule GO:1904115 - axon cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 628 Mm			1 89
+	Hs
		148059 DC1I1_HUMAN (1-628): 5.47e-133: 405: 95.50		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		148093 DC1I1_HUMAN (1-628): 5.47e-133: 405: 95.50		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		928281 DC1I2_HUMAN (1-628): 6.38e-123: 379: 75.71		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		1033319 DC1I2_HUMAN (1-628): 6.38e-123: 379: 75.71		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Dm
		1096026 DYIN_DROME (6-618): 8.49e-98: 314: 45.77		DYL1_DROME (1-89): 1.36e-46: 145: 94.38
+	Ce
		219878 O45087_CAEEL (7-619): 3.29e-96: 310: 35.51		DYL1_CAEEL (1-89): 8.25e-46: 143: 92.14
+	Hs
		928412 DC2I1_HUMAN (6-620): 3.02e-85: 289: 15.15		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		1261759 DC2I1_HUMAN (6-620): 3.02e-85: 289: 15.15		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		928277 STRN3_HUMAN (88-588): 1.23e-71: 248: 15.44		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		1022851 STRN3_HUMAN (88-588): 1.23e-71: 248: 15.44		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Cr
		65477 A8IJZ3_CHLRE (122-591): 8.63e-86: 280: 21.62		A8IRP4_CHLRE (13-88): 3.51e-26: 94.7: 43.37
+	Hs
		792964 LIS1_HUMAN (508-625): 1.99e-19: 92.9: 11.02		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		793023 LIS1_HUMAN (508-625): 1.99e-19: 92.9: 11.02		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26
+	Hs
		928426 DC2I2_HUMAN (258-504): 3.34e-13: 74.6: 15.00		DYL1_HUMAN (1-89): 1.96e-46: 145: 100.00
+	Hs
		1290452 DC2I2_HUMAN (258-504): 3.34e-13: 74.6: 15.00		DYL2_HUMAN (1-89): 1.68e-45: 142: 93.26