Interactor 1: DNM3A (O88508)
DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (Cysteine methyltransferase DNMT3A) (EC 2.1.1.-) (DNA methyltransferase MmuIIIA) (DNA MTase MmuIIIA) (M.MmuIIIA)
Gene: Dnmt3a

Interactor 2: SUZ12 (Q80U70)
Polycomb protein Suz12 (Suppressor of zeste 12 protein homolog)
Gene: SUZ12

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 24074865
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 908
Mm

1 741
+ Hs
+ Mm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024