HitPredict

Interactor 1: NEMO (O88522)
NF-kappa-B essential modulator (NEMO) (IkB kinase-associated protein 1) (IKKAP1) (mFIP-3) (Inhibitor of nuclear factor kappa-B kinase subunit gamma) (I-kappa-B kinase subunit gamma) (IKK-gamma) (IKKG) (IkB kinase subunit gamma) (NF-kappa-B essential modifier)
Gene: Ikbkg

Interactor 2: MAVS (Q8VCF0)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	23951545
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0035591 - signaling adaptor activity
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 412 Mm			1 503
+	Hs
		1190149 NEMO_HUMAN (1-412): 1.2e-68: 224: 86.40		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93
+	Hs
		1190052 OPTN_HUMAN (67-411): 1.74e-36: 142: 26.40		MAVS_HUMAN (1-501): 3.96e-51: 184: 45.93
+	Hs
		554389 NEMO_HUMAN (1-412): 1.2e-68: 224: 86.40		MUC1_HUMAN (117-489): 5.3e-13: 73.6: 11.95
+	Hs
		867114 OPTN_HUMAN (67-411): 1.74e-36: 142: 26.40		SC24C_HUMAN (94-481): 1.52e-19: 94.5: 11.95
+	Hs
		1186077 MY18A_HUMAN (33-384): 1.23e-29: 123: 17.26		MICA3_HUMAN (63-470): 9.25e-20: 95.2: 14.63
+	Hs
		203228 ITSN1_HUMAN (12-368): 5e-36: 142: 15.31		SYNJ1_HUMAN (144-502): 5.9e-13: 73.6: 10.80
+	Hs
		166049 ITSN1_HUMAN (12-368): 5e-36: 142: 15.31		SYNJ2_HUMAN (138-408): 2.09e-10: 65.4: 16.55
+	Hs
		166056 ITSN2_HUMAN (2-383): 8.92e-25: 109: 13.69		SYNJ2_HUMAN (138-408): 2.09e-10: 65.4: 16.55