HitPredict

Interactor 1: PARP2 (O88554)
Poly [ADP-ribose] polymerase 2 (PARP-2) (mPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (DNA ADP-ribosyltransferase PARP2) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) (Protein poly-ADP-ribosyltransferase PARP2) (EC 2.4.2.-)
Gene: PARP2

Interactor 2: PARP2 (O88554)
Poly [ADP-ribose] polymerase 2 (PARP-2) (mPARP-2) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 2) (ARTD2) (DNA ADP-ribosyltransferase PARP2) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 2) (ADPRT-2) (Poly[ADP-ribose] synthase 2) (pADPRT-2) (Protein poly-ADP-ribosyltransferase PARP2) (EC 2.4.2.-)
Gene: PARP2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 11948190
Identification Methods pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PARP~PARP, PARP~PARP_reg, PARP_reg~PARP_reg, PARP_reg~WGR
Common GO terms GO:0003682 - chromatin binding
GO:0003684 - damaged DNA binding
GO:0003950 - NAD+ ADP-ribosyltransferase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 23 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 559
Mm

1 559
+ Hs
+ Hs
+ At
+ At
+ At
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024