HitPredict

Interactor 1: CCG2 (O88602)
Voltage-dependent calcium channel gamma-2 subunit (Neuronal voltage-gated calcium channel gamma-2 subunit) (Stargazin) (Transmembrane AMPAR regulatory protein gamma-2) (TARP gamma-2)
Gene: Cacng2

Interactor 2: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.706

The method score is based on:

Property Details
Experiments 27507650, 28671696, 36417873, 36604605, 19455133
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0032281 - AMPA glutamate receptor complex
GO:0035255 - ionotropic glutamate receptor binding
GO:0044300 - cerebellar mossy fiber
GO:0098839 - postsynaptic density membrane
GO:0098970 - postsynaptic neurotransmitter receptor diffusion trapping
and 2 others

more...
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 323
Mm

1 724
+ Rn
+ Hs
+ Mm
+ Mm
+ Hs
+ Rn
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024