HitPredict

Interactor 1: HCN1 (O88704)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (Brain cyclic nucleotide-gated channel 1) (BCNG-1) (Hyperpolarization-activated cation channel 2) (HAC-2)
Gene: HCN1

Interactor 2: AP2S1 (P62743)
AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma-adaptin 3b) (Sigma2-adaptin)
Gene: AP2S1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0098978 - glutamatergic synapse
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 910 Mm			1 142
+	Hs
		239872 HCN1_HUMAN (1-910): 0: 666: 90.24		AP2S1_HUMAN (1-142): 6.18e-46: 147: 100.00
+	Hs
		240130 HCN1_HUMAN (1-910): 0: 666: 90.24		AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22