HitPredict

Interactor 1: PSMD1 (O88761)
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory subunit RPN2) (26S proteasome regulatory subunit S1) (26S proteasome subunit p112)
Gene: PSMD1

Interactor 2: UBC (Q63429)
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related]
Gene: UBC

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22871113
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PC_rep~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 953 Rn			1 810
+	Hs
		476252 PSMD1_HUMAN (1-953): 0: 1302: 98.64		UBC_HUMAN (1-533): 0: 662: 99.81
+	At
		221381 PSD1A_ARATH (1-950): 0: 1225: 48.61		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1092259 PSD1B_ARATH (1-950): 0: 1209: 48.30		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Hs
		475701 PSMD2_HUMAN (8-796): 0: 794: 18.73		UBC_HUMAN (1-533): 0: 662: 99.81
+	Hs
		924124 PSMD1_HUMAN (1-953): 0: 1302: 98.64		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Sp
		251843 RPN2_SCHPO (1-953): 0: 1036: 43.47		UBI4P_SCHPO (457-801): 1.39e-132: 401: 90.73
+	Mm
		476785 PSMD1_MOUSE (1-953): 0: 1303: 99.16		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		398072 PSMD1_HUMAN (1-953): 0: 1302: 98.64		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69
+	Sc
		477186 RPN2_YEAST (2-953): 0: 983: 40.06		UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73
+	At
		1091720 PSD2B_ARATH (8-796): 0: 744: 17.37		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	At
		1092336 PSD2A_ARATH (8-796): 0: 741: 17.73		UBQ3_ARATH (533-801): 1.64e-106: 330: 89.22
+	Hs
		923974 PSMD2_HUMAN (8-796): 0: 794: 18.73		RS27A_HUMAN (685-760): 5.08e-42: 152: 100.00
+	Mm
		476933 PSMD2_MOUSE (8-796): 0: 792: 18.73		UBC_MOUSE (1-108): 6.19e-31: 132: 90.74
+	Hs
		397947 PSMD2_HUMAN (8-796): 0: 794: 18.73		ISG15_HUMAN (228-380): 7.21e-29: 115: 32.69
+	Sc
		477264 RPN1_YEAST (8-604): 7.8e-144: 455: 16.09		UBI4P_YEAST (457-801): 3.68e-132: 400: 90.73
+	Ce
		477558 Q9GZH5_CAEEL (615-798): 8.02e-53: 202: 18.00		UBIQ1_CAEEL (1-229): 1.94e-85: 291: 98.25