HitPredict

Interactor 1: STAM2 (O88811)
Signal transducing adapter molecule 2 (STAM-2) (Hrs-binding protein)
Gene: STAM2

Interactor 2: UBP8 (Q80U87)
Ubiquitin carboxyl-terminal hydrolase 8 (EC 3.4.19.12) (Deubiquitinating enzyme 8) (Ubiquitin isopeptidase Y) (mUBPy) (Ubiquitin thioesterase 8) (Ubiquitin-specific-processing protease 8)
Gene: Usp8

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	20130268, 10982817
Identification Methods	affinity chromatography technology, coimmunoprecipitation, filter binding
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 523 Mm			1 1080
+	Hs
		277018 STAM2_HUMAN (1-523): 8.19e-138: 410: 86.10		UBP8_HUMAN (1-1080): 0: 679: 80.86
+	Hs
		777061 STAM1_HUMAN (1-507): 2.71e-110: 340: 54.41		UBP8_HUMAN (1-1080): 0: 679: 80.86
+	Mm
		292688 GRAP2_MOUSE (202-256): 2.67e-12: 69.7: 55.17		UBP8_MOUSE (1-1080): 0: 721: 100.00
+	Mm
		1141140 GRB2_MOUSE (207-257): 1.2e-12: 68.9: 54.90		UBP8_MOUSE (1-1080): 0: 721: 100.00
+	Hs
		275176 GRAP2_HUMAN (202-256): 1.14e-12: 70.9: 56.90		UBP8_HUMAN (1-1080): 0: 679: 80.86
+	Hs
		777028 GRB2_HUMAN (207-257): 1.22e-12: 68.9: 54.90		UBP8_HUMAN (1-1080): 0: 679: 80.86
+	Dm
		1280443 HRS_DROME (7-158): 6.34e-44: 167: 26.97		Q9VDD8_DROME (407-1078): 2.99e-109: 363: 27.06
+	Hs
		1270632 STAM1_HUMAN (1-507): 2.71e-110: 340: 54.41		UBP15_HUMAN (926-1068): 1.12e-34: 145: 49.65
+	Hs
		259274 GRB2_HUMAN (207-257): 1.22e-12: 68.9: 54.90		UBP12_HUMAN (701-1072): 2.62e-107: 341: 25.71