Interactor 1: CRADD (O88843)
Death domain-containing protein CRADD (Caspase and RIP adapter with death domain) (RIP-associated protein with a death domain)
Gene: CRADD
Interactor 2: CASP2 (P29594)
Caspase-2 (CASP-2) (EC 3.4.22.55) (Neural precursor cell expressed developmentally down-regulated protein 2) (NEDD-2) (Protease ICH-1) [Cleaved into: Caspase-2 subunit p18; Caspase-2 subunit p13; Caspase-2 subunit p12]
Gene: CASP2
Species: Mus musculus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11978827 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD, CARD~Death |
| Common GO terms | GO:0005634 - nucleus GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0006974 - DNA damage response GO:0006977 - DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest and 5 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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| + | Hs |   |
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| + | Rn |  |
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
