HitPredict

Interactor 1: SH21A (O88890)
SH2 domain-containing protein 1A (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: Sh2d1a

Interactor 2: KPCT (Q02111)
Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)
Gene: Prkcq

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	20668219
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~SH2
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 126 Mm			1 707
+	Hs
		411685 LCK_HUMAN (1-124): 8.45e-41: 143: 20.77		KPCT_HUMAN (1-706): 0: 824: 94.76
+	Hs
		412141 FYN_HUMAN (1-124): 5.8e-37: 133: 18.66		KPCT_HUMAN (1-706): 0: 824: 94.76
+	Hs
		412145 FYN_HUMAN (1-124): 5.8e-37: 133: 18.66		KPCD_HUMAN (1-705): 0: 776: 61.14
+	Hs
		522929 SRC_HUMAN (1-124): 6.63e-37: 133: 22.90		KPCD_HUMAN (1-705): 0: 776: 61.14
+	Hs
		984521 SHIP1_HUMAN (6-126): 3.99e-34: 126: 38.84		KPCD_HUMAN (1-705): 0: 776: 61.14
+	Hs
		337439 ABL1_HUMAN (1-124): 5.64e-34: 125: 25.00		KPCD_HUMAN (1-705): 0: 776: 61.14
+	Mm
		411915 LCK_MOUSE (1-124): 1.07e-40: 142: 20.77		KPCE_MOUSE (21-696): 0: 695: 41.14
+	Mm
		403411 SRC_MOUSE (1-124): 6.92e-37: 132: 22.90		KPCE_MOUSE (21-696): 0: 695: 41.14
+	Hs
		412067 FYN_HUMAN (1-124): 5.8e-37: 133: 18.66		KPCI_HUMAN (57-703): 0: 547: 27.69
+	Hs
		522928 SRC_HUMAN (1-124): 6.63e-37: 133: 22.90		KPCZ_HUMAN (58-703): 5.44e-179: 524: 28.72
+	Hs
		337438 ABL1_HUMAN (1-124): 5.64e-34: 125: 25.00		KPCZ_HUMAN (58-703): 5.44e-179: 524: 28.72
+	Hs
		433609 LYN_HUMAN (1-124): 3.9e-39: 138: 19.23		AKT2_HUMAN (273-699): 8.21e-153: 453: 34.94
+	Hs
		412046 FYN_HUMAN (1-124): 5.8e-37: 133: 18.66		AKT1_HUMAN (320-700): 1.8e-150: 447: 40.26
+	Hs
		522810 SRC_HUMAN (1-124): 6.63e-37: 133: 22.90		AKT1_HUMAN (320-700): 1.8e-150: 447: 40.26
+	Mm
		403418 SRC_MOUSE (1-124): 6.92e-37: 132: 22.90		AKT1_MOUSE (253-699): 3.35e-150: 447: 35.95
+	Hs
		681710 CSK_HUMAN (1-124): 2.89e-35: 127: 25.00		AKT1_HUMAN (320-700): 1.8e-150: 447: 40.26
+	Dm
		1213395 Q9VGK8_DROME (1-104): 4.49e-24: 97.8: 27.89		AKT1_DROME (368-696): 1.32e-147: 445: 45.37
+	Mm
		593485 GRB2_MOUSE (1-114): 1.31e-33: 118: 24.56		KPCA_MOUSE (131-406): 3.34e-41: 162: 26.94
+	Hs
		408528 LYN_HUMAN (1-124): 3.9e-39: 138: 19.23		KPCB_HUMAN (206-315): 5.34e-09: 61.6: 22.22