HitPredict

Interactor 1: SH21A (O88890)
SH2 domain-containing protein 1A (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: Sh2d1a

Interactor 2: SLAF1 (Q9QUM4)
Signaling lymphocytic activation molecule (SLAM family member 1) (CD antigen CD150)
Gene: Slamf1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	19151721, 12545173, 11477403, 16847311
Identification Methods	anti bait coimmunoprecipitation, pull down, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002250 - adaptive immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Mm			1 343
+	Mm
		1322348 SHIP1_MOUSE (5-126): 1.89e-37: 135: 36.89		SLAF1_MOUSE (1-343): 6.54e-96: 289: 100.00
+	Mm
		763408 FYN_MOUSE (1-124): 5.46e-37: 133: 18.66		SLAF1_MOUSE (1-343): 6.54e-96: 289: 100.00
+	Hs
		412176 FYN_HUMAN (1-124): 5.8e-37: 133: 18.66		SLAF1_HUMAN (1-343): 4.59e-87: 267: 60.64
+	Hs
		454828 FGR_HUMAN (1-124): 2.1e-36: 131: 22.14		SLAF1_HUMAN (1-343): 4.59e-87: 267: 60.64
+	Hs
		155840 SH21B_HUMAN (5-107): 8.41e-38: 126: 45.63		SLAF1_HUMAN (1-343): 4.59e-87: 267: 60.64
+	Hs
		411547 LCK_HUMAN (1-124): 8.45e-41: 143: 20.77		CD2_HUMAN (14-323): 1.55e-51: 176: 18.87
+	Hs
		411939 FYN_HUMAN (1-124): 5.8e-37: 133: 18.66		CD2_HUMAN (14-323): 1.55e-51: 176: 18.87
+	Hs
		176495 SHIP2_HUMAN (3-120): 7.95e-40: 142: 42.37		CD244_HUMAN (32-339): 2.47e-45: 160: 20.25
+	Hs
		411818 LCK_HUMAN (1-124): 8.45e-41: 143: 20.77		SLAF6_HUMAN (13-338): 4.66e-42: 150: 19.88
+	Hs
		412347 FYN_HUMAN (1-124): 5.8e-37: 133: 18.66		CD244_HUMAN (32-339): 2.47e-45: 160: 20.25
+	Hs
		523136 SRC_HUMAN (1-124): 6.63e-37: 133: 22.90		CD244_HUMAN (32-339): 2.47e-45: 160: 20.25
+	Hs
		789096 ABL2_HUMAN (1-124): 3.5e-35: 129: 25.78		SLAF5_HUMAN (12-339): 4.23e-47: 164: 20.46
+	Hs
		411561 LCK_HUMAN (1-124): 8.45e-41: 143: 20.77		CD48_HUMAN (47-260): 4.87e-41: 145: 21.30
+	Hs
		433317 YES_HUMAN (1-124): 6.35e-39: 138: 20.61		CXAR_HUMAN (10-339): 2.35e-41: 149: 13.74
+	Hs
		433691 LYN_HUMAN (1-124): 3.9e-39: 138: 19.23		CXAR_HUMAN (10-339): 2.35e-41: 149: 13.74
+	Hs
		782823 CSK_HUMAN (1-124): 2.89e-35: 127: 25.00		CD244_HUMAN (32-339): 2.47e-45: 160: 20.25
+	Hs
		522764 SRC_HUMAN (1-124): 6.63e-37: 133: 22.90		CD33_HUMAN (35-330): 3.38e-41: 149: 15.99
+	Hs
		523015 SRC_HUMAN (1-124): 6.63e-37: 133: 22.90		CEA21_HUMAN (9-301): 2.17e-34: 129: 16.83
+	Hs
		433742 LYN_HUMAN (1-124): 3.9e-39: 138: 19.23		PTK7_HUMAN (48-327): 4.46e-19: 90.3: 8.19
+	Hs
		523003 SRC_HUMAN (1-124): 6.63e-37: 133: 22.90		MYLK_HUMAN (141-230): 2.28e-10: 64.2: 16.50