Interactor 1: GRB14 (O88900)
Growth factor receptor-bound protein 14 (GRB14 adapter protein)
Gene: GRB14
Interactor 2: IRS1 (P35570)
Insulin receptor substrate 1 (IRS-1) (pp185)
Gene: IRS1
Species: Rattus norvegicus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15924411 |
| Identification Methods | anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IRS~PH, PH~PH, PH~RA |
| Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0008286 - insulin receptor signaling pathway GO:0030674 - protein-macromolecule adaptor activity GO:0032869 - cellular response to insulin stimulus and 2 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
