HitPredict

Interactor 1: LIN7C (O88952)
Protein lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Interactor 2: PALS1 (Q9JLB2)
Protein PALS1 (MAGUK p55 subfamily member 5) (Protein associated with Lin-7 1)
Gene: PALS1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	16186258
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	L27~L27, Guanylate_kin~PDZ, PDZ~PDZ, PDZ~SH3_2
Common GO terms	GO:0002011 - morphogenesis of an epithelial sheet GO:0005923 - bicellular tight junction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 197 Mm			1 675
+	Hs
		1232510 LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00		PALS1_HUMAN (1-675): 0: 568: 96.74
+	Hs
		1232501 LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69		PALS1_HUMAN (1-675): 0: 568: 96.74
+	Hs
		159277 LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00		CSKP_HUMAN (9-674): 1.69e-142: 440: 26.40
+	Mm
		251090 LIN7C_MOUSE (1-197): 1.38e-57: 181: 100.00		CSKP_MOUSE (9-674): 2.09e-142: 440: 26.40
+	Hs
		159269 LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69		CSKP_HUMAN (9-674): 1.69e-142: 440: 26.40
+	Mm
		251089 LIN7B_MOUSE (1-196): 4.08e-55: 175: 85.71		CSKP_MOUSE (9-674): 2.09e-142: 440: 26.40
+	Hs
		1346107 LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00		PALS2_HUMAN (124-674): 9.86e-144: 431: 34.40
+	Hs
		1050418 LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00		MPP2_HUMAN (140-674): 7.23e-143: 430: 33.04
+	Hs
		1334778 LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69		PALS2_HUMAN (124-674): 9.86e-144: 431: 34.40
+	Hs
		1050415 LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69		MPP2_HUMAN (140-674): 7.23e-143: 430: 33.04
+	Hs
		1132897 LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00		MPP7_HUMAN (122-674): 3.46e-124: 382: 35.89
+	Hs
		1032762 LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00		MPP3_HUMAN (118-675): 1.44e-122: 378: 32.72
+	Hs
		1132892 LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69		MPP7_HUMAN (122-674): 3.46e-124: 382: 35.89
+	Hs
		1032760 LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69		MPP3_HUMAN (118-675): 1.44e-122: 378: 32.72
+	Hs
		942387 LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00		DLG4_HUMAN (214-344): 1.16e-17: 89.3: 14.39
+	Hs
		1021573 LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00		DLG1_HUMAN (53-344): 1.22e-16: 86.2: 13.74
+	Mm
		292491 LIN7C_MOUSE (1-197): 1.38e-57: 181: 100.00		DLG1_MOUSE (69-344): 3.16e-16: 85.1: 13.03
+	Hs
		942382 LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69		DLG4_HUMAN (214-344): 1.16e-17: 89.3: 14.39
+	Rn
		677810 LIN7B_RAT (1-196): 7.76e-55: 174: 85.71		DLG4_RAT (214-344): 1.05e-17: 89.3: 14.39
+	Hs
		1021563 LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69		DLG1_HUMAN (53-344): 1.22e-16: 86.2: 13.74