HitPredict

Interactor 1: MPP3 (O88954)
MAGUK p55 subfamily member 3 (Discs large homolog 3) (Protein MPP3)
Gene: MPP3

Interactor 2: DLG1 (Q62696)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97)
Gene: DLG1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	12351654
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Guanylate_kin~Guanylate_kin, Guanylate_kin~PDZ, Guanylate_kin~SH3_1, L27~L27_1, PDZ~PDZ, Guanylate_kin~SH3_2, PDZ~SH3_2, SH3_1~SH3_2
Common GO terms	GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0016324 - apical plasma membrane GO:0030165 - PDZ domain binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 585 Rn			1 911
+	Rn
		1144009 CSKP_RAT (1-584): 1.43e-121: 382: 27.22		DLG1_RAT (1-911): 0: 732: 100.00
+	Hs
		1021489 MPP2_HUMAN (1-584): 4.74e-135: 407: 29.55		DLG1_HUMAN (1-911): 0: 705: 92.22
+	Mm
		251104 CSKP_MOUSE (1-584): 1.11e-122: 385: 26.86		DLG1_MOUSE (1-911): 0: 719: 95.40
+	Hs
		159200 CSKP_HUMAN (1-584): 5.98e-123: 386: 26.86		DLG1_HUMAN (1-911): 0: 705: 92.22
+	Dm
		53136 A1Z8G0_DROME (3-585): 9.82e-139: 417: 37.15		DLG1_DROME (1-911): 0: 582: 48.53
+	Hs
		159249 CSKP_HUMAN (1-584): 5.98e-123: 386: 26.86		DLG3_HUMAN (107-911): 0: 586: 62.56
+	Rn
		1144014 DLG2_RAT (47-422): 2.83e-23: 106: 11.52		DLG1_RAT (1-911): 0: 732: 100.00
+	Hs
		1050419 MPP2_HUMAN (1-584): 4.74e-135: 407: 29.55		PALS2_HUMAN (337-906): 4.94e-112: 356: 21.20
+	Mm
		936188 DLG2_MOUSE (47-422): 3.59e-23: 106: 11.52		DLG3_MOUSE (107-911): 0: 590: 62.87
+	Ce
		105560 Q17549_CAEEL (147-583): 9.29e-55: 198: 29.08		DLG1_CAEEL (5-906): 8.91e-127: 408: 33.10
+	Hs
		1295085 MPP4_HUMAN (9-584): 2.45e-145: 436: 36.74		MPP4_HUMAN (156-376): 6.87e-19: 93.7: 12.56
+	Mm
		1143555 MPP2_MOUSE (1-584): 3.4e-134: 404: 31.26		DLG4_MOUSE (157-406): 3.36e-24: 111: 22.71
+	Hs
		1232493 MPP4_HUMAN (9-584): 2.45e-145: 436: 36.74		PALS1_HUMAN (183-355): 1.9e-10: 66.7: 13.19
+	Hs
		159110 CSKP_HUMAN (1-584): 5.98e-123: 386: 26.86		CSKP_HUMAN (12-429): 5.61e-25: 114: 12.10
+	Hs
		159190 CSKP_HUMAN (1-584): 5.98e-123: 386: 26.86		DLG4_HUMAN (157-406): 3.82e-24: 111: 22.71
+	Hs
		942325 EM55_HUMAN (77-584): 1.07e-110: 340: 28.38		DLG4_HUMAN (157-406): 3.82e-24: 111: 22.71
+	Hs
		1232481 PALS1_HUMAN (24-585): 7.1e-122: 376: 34.39		PALS1_HUMAN (183-355): 1.9e-10: 66.7: 13.19
+	Mm
		1143467 DLG2_MOUSE (47-422): 3.59e-23: 106: 11.52		DLG4_MOUSE (157-406): 3.36e-24: 111: 22.71